The Analgesic Effect and Safety of Ropivacaine Combined with Dexmedetomidine in Delivery of Pregnant Women with Gestational Hypertension
Objective To analyze the effectiveness and safety of ropivacaine combined with dexmedetomidine for labor analgesia in women with gestational hypertension. Methods From January 2022 to December 2023,108 pregnant women with gestational hypertension were selected as the study subjects and randomly divided into an observation group and a control group,with 54 cases in each group. The control group patients were given ropivacaine alone during delivery,while the observation group patients were given a combination of ropivacaine and dexmedetomidine for pain relief during delivery. The pain and sedation scores of the observation group and the control group patients at various time points were statistically compared,and the relevant indicators during delivery and the incidence of adverse reactions during analgesia were statis-tically analyzed. Results The Visual Analogue Scale (VAS) score,first stage of labor time,and bleeding volume of the observation group were lower than those of the control group at 15 minutes of analgesia (T1),60 minutes of analgesia (T2),full opening of the cervix (T3),and delivery of the fetus (T4) (P<0.05),and the Ramsay sedation score was higher than that of the control group at T1 to T4 (P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the observation group and the control group during treatment (P>0.05). Conclusion The combination of ropiv-acaine and dexmedetomidine demonstrated excellent analgesic and sedative effects on pregnant women with gestational hy-pertension,shortened the first stage of labor,reduced bleeding,and had no adverse effects on the Apgar score of newborns. It was safe and reliable,and is recommended for clinical promotion and application.
万方数据
维普
