Retrospective Analysis of Adverse Drug Reactions in 1512 Hospitalized Patients at Sunshine Ronghe Hospital
Objective To analyze the adverse drug reactions of hospitalized patients and provide a reference for rational drug use in clinical practice. Methods A total of 1512 hospitalized adverse drug reaction (ADR) reports sub-mitted to the National Center for Adverse Drug Reaction Monitoring from January 2021 to December 2023 were collected,including 882 males and 630 females;499 ADR cases were reported in 2021,541 ADR cases were reported in 2022,and 472 ADR cases were reported in 2023. The types of drugs involved,the route of administration,the distribution of involved systems,and the gender and age differences of patients with ADR in different years were analyzed. Results The types of drugs involved were mainly antitumor drugs,anti-infective drugs,and cardiovascular system drugs,accounting for 25.60％,23.88％,and 17.53％,respectively;the main routes of administration were oral administration and intravenous drip,account-ing for 46.43％ and 36.24％,respectively;the involved systems were mainly gastrointestinal and digestive systems and skin,accounting for 43.39％ and 16.53％,respectively;there was no significant difference in the gender and age of inpatients with adverse drug reactions in 2021,2022,and 2023 ( P>0.05 ). Conclusion The monitoring and reporting of ADR should be strengthened. At the same time,attention should be paid to the monitoring of adverse drug reactions associated with antitu-mor drugs,anti-infective drugs,and cardiovascular system drugs.
Drug-related side effects and adverse reactionsRetrospective study
万方数据
维普
