首页|抗苗勒管激素及性激素指标联合卵巢超声指标对多囊卵巢综合征不孕的诊断价值

抗苗勒管激素及性激素指标联合卵巢超声指标对多囊卵巢综合征不孕的诊断价值

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目的 分析抗苗勒管激素(AMH)及性激素指标联合卵巢超声指标在多囊卵巢综合征(PCOS)不孕中的诊断价值.方法 选取2020年10月至2023年10月湖南中医药大学第一附属医院妇产科101例PCOS不孕患者作为研究组,并选取同期开展孕前检查的健康女性101例作为对照组,比较2组血清学指标及性激素指标联合卵巢超声指标,并分析其联合对PCOS不孕患者的诊断价值.结果 与对照组比较,研究组抗苗勒管激素(AMH)、雌二醇(E2)、黄体生成激素(LH)、睾酮(T)、血管化血流指数(VFI)、血流指数(PI)、血管化指数(VI)更高(P<0.05),研究组卵泡刺激素(FSH)更低(P<0.05).受试者工作特征(ROC)曲线分析显示,AMH、FSH、E2、LH、T、VFI、PI、VI、联合诊断PCOS不孕的曲线下面积(AUC)分别为0.776、0.740、0.750、0.764、0.767、0.785、0.697、0.744、0.978,在最佳截断值对应的敏感度分别为54.5%、100.0%、49.5%、52.5%、53.5%、57.4%、44.6%、100.0%、88.1%,特异度分别为100.0%、50.5%、100.0%、100.0%、100.0%、100.0%、90.1%、47.5%、95.0%.联合诊断PCOS不孕的AUC高于AMH、FSH、E2、LH、T、VFI、PI、VI单独检测.结论 AMH及性激素指标联合卵巢超声指标对PCOS不孕患者具有较高的诊断价值.
Diagnostic Value of Serological Index,Sex Hormone Index Combined with Ovarian Ultrasound Index in Infertility with Polycystic Ovary Syndrome
Objective To analyze the diagnostic value of serological indicators,sex hormone indicators combined with ovarian ultrasound indicators in polycystic ovary syndrome (PCOS) infertility. Methods From October 2020 to October 2023,101 infertile women with PCOS were selected as the research group,and 101 healthy women who underwent pre-pregnancy exam-ination in the same period were selected as the control group. The serological index and sex hormone index combined with ovarian ultrasound index were compared between the two groups,and the diagnostic value of their combination in infertile women with PCOS was analyzed. Results Compared with the control group,the anti-Mullerian hormone (AMH),estradiol (E2),luteinizing hormone (LH),testosterone (T),vascularized blood flow index (VFI),blood flow index (PI) and vascularized index (VI) in the study group were higher (P<0.05),while follicle-stimulating hormone (FSH) in the study group was lower (P<0.05). ROC curve analysis showed that the AUC of AMH,FSH,E2,LH,T,VFI,PI,VI and the combined diagnosis of PCOS infertility were 0.776,0.74,0.75,0.764,0.767,0.785,0.697,0.744 and 0.978,respectively. The sensitivity corresponding to the optimal critical value is 54.5%,100.0%,49.5%,52.5%,53.5%,57.4%,44.6%,100.0%,88.1%,and the specificity is 100.0%、50.5%、100.0%、100.0%、100.0%、100.0%、90.1%、47.5%、95.0% respectively. The AUC of the combined diagnostic model for PCOSrelated infertil-ity was higher than that of individual indicators such as AMH,FSH,E2,LH,VFI,PI,and VI. Conclusion Se-rological indexes,sex hormone indexes combined with ovarian ultrasound indexes have high diagnostic value for PCOS infertility patients.

Serological indicatorsSex hormone indexOvarian ultrasound indexInfertility due to polycystic ovary syndromeDiagnostic value

邓敏英、张勇、龚月秋

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100191 湖南 长沙,湖南中医药大学第一附属医院妇产科

413000 湖南 益阳,湖南省益阳市第五人民医院医技科

抗苗勒氏管激素 性激素 超声检查 多囊卵巢综合征 不孕 诊断价值

2024

转化医学杂志
海军总医院

转化医学杂志

CSTPCD
影响因子:0.671
ISSN:2095-3097
年,卷(期):2024.13(5)