首页|HACOR评分评估经鼻高流量氧疗的急性呼吸衰竭患者疗效的应用价值

HACOR评分评估经鼻高流量氧疗的急性呼吸衰竭患者疗效的应用价值

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目的 研究HACOR评分评估经鼻高流量氧疗(HFNC)的急性呼吸衰竭患者疗效的应用价值.方法 回顾性选取2022年1月至2023年12月在徐州医科大学附属沭阳医院接受HFNC的急性呼吸衰竭患者136例为研究对象,根据治疗效果分为有效组104例和无效组32例.比较2组患者的一般资料、生理学参数、APACHE Ⅱ评分、ROX指数、HACOR评分等的差异,建立初始选择HFNC时预测其疗效的Logistic回归模型;运用受试者工作特征(ROC)曲线比较治疗过程中ROX指数、HACOR评分的价值.结果 有效组基线心率(HR)、呼吸频率(RR)、APACHE Ⅱ评分及HACOR评分低于无效组,有效组基线氧合指数、ROX指数高于无效组,比较差异均有统计学意义(P值均<0.05).多因素分析显示,氧合指数升高是HFNC治疗有效的保护因素,APACHE Ⅱ评分、HACOR评分升高则是危险因素.ROX指数在HFNC治疗后2、6、12 h预测其结局的曲线下面积(AUC)值依次为:0.67、0.73、0.80.HACOR评分在HFNC治疗后2、6、12 h预测其结局的AUC值依次为:0.72、0.80、0.83.结论 HACOR评分具有较高的预测价值,且随时间延长,预测价值升高.
The Potential Value of Hacor Score to Evaluate the Efficacy of Nasal High-Flow Oxygen Therapy in Patients with Acute Respiratory Failure
Objective To explore the potential value of HACOR score in evaluating the efficacy of high-flow nasal can-nula oxygen therapy (HFNC) in patients with acute respiratory failure. Methods A total of 136 patients with acute respiratory failure who received HFNC in Shuyang Hospital Affiliated to Xuzhou Medical University from January 2022 to December 2023 were retrospectively selected as the research objects. According to the treatment effect,they were divided into an effective group (104 cases) and an ineffective group (32 cases). The differences in general data,physiological parameters,APACHE Ⅱ score,ROX index,and HACOR score between the two groups were compared,and a Logistic regression model was established to predict the efficacy of HFNC during the initial stage. Receiver operating characteristic (ROC) curve analysis was used to compare the predictive value of ROX index and HACOR score during treatment. Results The baseline HR,RR,APACHE Ⅱ score,and HACOR score were lower than those of the ineffective group,while the baseline oxygenation index and ROX index were higher in the effective group,and the differences were statistically significant (all P<0.05). Multivariate analysis showed that an increased oxygenation index was a protective factor for HFNC treatment efficacy,where-as increased APACHE Ⅱ and HACOR scores were risk factors. The AUC values of the ROX index for predicting HFNC treatment outcomes at 2,6,and 12 hours were 0.67,0.73,and 0.80,respectively. The AUC values of HACOR score for predicting outcomes at 2,6,and 12 hours were 0.72,0.80,and 0.83,respectively. Conclusion HA-COR score has a high predictive value,and its predictive accuracy increases over time.

High-flow nasal cannulaAcute re-spiratory failureTherapeutic effectROX indexHACOR scorePredictive value

石小坚、顾媛媛、宋小路、燕宪亮

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221004 江苏 徐州,徐州医科大学第二临床医学院

223600 江苏 沭阳,徐州医科大学附属沭阳医院

221200 江苏 睢宁,江苏省睢宁县人民医院

221006 江苏 徐州,徐州医科大学附属医院

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经鼻高流量氧疗 急性呼吸衰竭 治疗效果 ROX指数 HACOR评分 预测价值

2024

转化医学杂志
海军总医院

转化医学杂志

CSTPCD
影响因子:0.671
ISSN:2095-3097
年,卷(期):2024.13(5)