The Potential Value of Hacor Score to Evaluate the Efficacy of Nasal High-Flow Oxygen Therapy in Patients with Acute Respiratory Failure
Objective To explore the potential value of HACOR score in evaluating the efficacy of high-flow nasal can-nula oxygen therapy (HFNC) in patients with acute respiratory failure. Methods A total of 136 patients with acute respiratory failure who received HFNC in Shuyang Hospital Affiliated to Xuzhou Medical University from January 2022 to December 2023 were retrospectively selected as the research objects. According to the treatment effect,they were divided into an effective group (104 cases) and an ineffective group (32 cases). The differences in general data,physiological parameters,APACHE Ⅱ score,ROX index,and HACOR score between the two groups were compared,and a Logistic regression model was established to predict the efficacy of HFNC during the initial stage. Receiver operating characteristic (ROC) curve analysis was used to compare the predictive value of ROX index and HACOR score during treatment. Results The baseline HR,RR,APACHE Ⅱ score,and HACOR score were lower than those of the ineffective group,while the baseline oxygenation index and ROX index were higher in the effective group,and the differences were statistically significant (all P<0.05). Multivariate analysis showed that an increased oxygenation index was a protective factor for HFNC treatment efficacy,where-as increased APACHE Ⅱ and HACOR scores were risk factors. The AUC values of the ROX index for predicting HFNC treatment outcomes at 2,6,and 12 hours were 0.67,0.73,and 0.80,respectively. The AUC values of HACOR score for predicting outcomes at 2,6,and 12 hours were 0.72,0.80,and 0.83,respectively. Conclusion HA-COR score has a high predictive value,and its predictive accuracy increases over time.
High-flow nasal cannulaAcute re-spiratory failureTherapeutic effectROX indexHACOR scorePredictive value