Relationship Between Quantitative Ultrasound Parameters and Recurrence and Metastasis of Breast Cancer After Modified Radical Mastectomy
Objective To explore the relationship between quantitative ultrasound parameters and postoperative re-currence and metastasis in breast cancer patients. Methods A total of 120 patients who underwent radical mastectomy at Nanjing Central Hospital and Nanjing Drum Tower Hospital from May 2020 to May 2023 were randomly selected for retrospec-tive analysis. According to the recurrence and metastasis status,the recurrence and metastasis group and the non-recurrence and metastasis group were comprised of 42 and 78 cases,respectively. The clinical data and quantitative ultrasound parameters such as peak intensity (PI),maximum blood flow velocity (Vmax),and resistance index (RI) were compared between the two groups. The relationship and predictive value of PI,Vmax,and RI for postoperative recurrence and metastasis were analyzed using multivari-ate logistic regression and receiver operating characteristic (ROC) curve analysis. Results Compared with the non-recurrence and metastasis group,the PI,Vmax,RI levels,tumor diameter>5 cm,and lymph node metastasis rate were significantly increased in the recurrence and metastasis group (P<0.05);Tumor diameter>5 cm,lymph node metastasis,increased Vmax,increased RI,and increased PI were independent risk factors for recurrence and metastasis of breast cancer patients after modified radical mastecto-my (P<0.05). The area under the diagnostic curve (AUC) of the combined detection of PI,Vmax,and RI for the recurrence and me-tastasis of breast cancer patients after modified radical mastectomy was significantly higher than that of single detection (P<0.05). Conclusion Quantitative ultrasound parameters are influencing factors for recurrence and metastasis of breast cancer patients af-ter modified radical mastectomy. These parameters can be used as clinical prediction indicators and have high application value.
Breast cancerBreast ultrasoundMaximum blood flow velocityPeak intensityResistance indexRecurrence and metastasisReceiver operating characteristic curve
万方数据
维普
