Effects of Limbal Stem Cell Transplantation Combined with Surgical Exci-sion Treatment on Corneal Dispersion,Visual Acuity and Tear Film Func-tion in Patients with Pterygium
Objective To investigate the effects of limbal stem cell transplantation combined with surgical excision treatment on corneal dispersion,visual acuity and tear film function in patients with pterygium.Methods 119 cases of pte-rygium treated in department of ophthalmology,Deyu medical Ma,anshan general hospital from June 2019 to June 2024 were selected,and according to different surgical treatment methods,they were divided into experimental group(limbal stem cell transplantation combined with surgical excision,n=60)and control group(surgical excision,n=59).The general data,clinical efficacy,keratoluminosity,visual acuity,tear film function level before and after treatment and the incidence of com-plications after treatment of the experimental group and the control group were compared.Results Compared between the two groups,the proportion of total effective rate of the experimental group was higher than that of the control group(P＜0.05).Compared with before treatment,corneal diffuser of experimental group and control group decreased and visual acuity level in-creased,and corneal diffuser level of experimental group was lower than control group,visual acuity level was higher than con-trol group(P＜0.05).Compared with before treatment,the tear film rupture time and tear secretion time of the experimental group and the control group were prolonged,and the film rupture time and tear secretion time of the experimental group were longer than that of the control group(P＜0.05).Compared between the two groups,the total number of adverse reactions such as infection,scleral necrosis,lysis and softening in the experimental group was lower than that in the control group(P＜0.05).Conclusion Limbal stem cell transplantation combined with surgical excision for patients with pterygium can improve the clinical therapeutic effect,improve the level of corneal refraction,vision and tear film function,and reduce the incidence of complications such as infection,scleral necrosis and lysis and malacia,which is safe and worthy of clinical promotion.
Pterygium patientsLimbal stem cell transplantation combined with surgical excisionCorneal diffusivi-tyEyesightTear film function
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