首页|基于倾向性评分匹配研究比较经颏下入路与经口腔前庭入路腔镜手术治疗甲状腺微小乳头状癌的效果及安全性

基于倾向性评分匹配研究比较经颏下入路与经口腔前庭入路腔镜手术治疗甲状腺微小乳头状癌的效果及安全性

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目的 基于倾向性评分匹配研究比较经颏下入路与经口腔前庭入路腔镜手术治疗甲状腺微小乳头状癌的有效性及安全性.方法 纳入2022 年1 月至2023 年12 月择期手术的 150 例甲状腺微小乳头状癌患者临床资料.根据手术方案分为口腔组85 例和颏下组65 例.以倾向性评分匹配法按1∶1 比例匹配均衡治疗前混杂因素,最终2 组各有48 例匹配成功.比较2 组围术期指标、疼痛程度、美观度、并发症及复发率.结果 颏下组手术时长短于口腔组(P<0.05).2 组术中出血量、中央区淋巴结清扫数目、术后24h引流量、住院时间对比均无统计学差异(P>0.05).术后 24 h,颏下组视觉模拟评分法(VAS)评分较口腔组更低(P<0.05).术后72 h,2 组VAS评分比较无统计学差异(P>0.05).术后1、3 个月,口腔组温哥华瘢痕评定量表评分低于颏下组(P<0.05).2 组并发症发生率、复发率对比无统计学差异(P>0.05).结论 经口腔前庭入路与经颏下入路腔镜甲状腺切除术治疗甲状腺微小乳头状癌具有相似的手术效果,经口腔前庭入路腔镜甲状腺切除术美观度更好,而经颏下入路腔镜甲状腺切除术疼痛程度更低、手术时间更短.
Comparison of the Efficacy and Safety of Endoscopic Surgery for Thyroid Papillary Carcinoma Through Submental and Oral Vestibular Approaches Based on Propensity Score Matching Study
Objective To compare the effectiveness and safety of endoscopic surgery for thyroid papillary carcinoma through submental and oral vestibular approaches based on propensity score matching.Methods Clinical data of 150 patients with thyroid micropapillary carcinoma undergoing elective surgery from January 2022 to December 2023 were included.Ac-cording to the operation plan,85 cases were divided into oral group and 65 cases were submental group.Propensity score matching method was used to match the confounding factors before balanced treatment at a ratio of 1∶1,and 48 cases in each group were successfully matched.Perioperative indexes,pain degree,aesthetics,complications and recurrence rate were com-pared between the two groups.Results The length of operation in submental group was longer than that in oral group(P<0.05).There were no significant differences in intraoperative blood loss,number of central lymph nodes dissection,24 h postoperative drainage volume and length of hospital stay between the two groups(P>0.05).24 h after surgery,the submen-tal pain visual analogue scale(VAS)score was lower than that of oral group(P<0.05).72 h after operation,there was no significant difference in pain VAS score between the two groups(P>0.05).At 1 and 3 months after surgery,the Vancouver Scar Rating Scale score of oral group was lower than that of submental group(P<0.05).There was no significant difference in complication rate and recurrence rate between 2 groups(P>0.05).Conclusion Endoscopic thyroidectomy through oral vestibular approach and submental approach have similar results in the treatment of minimal papillary thyroid carcinoma.En-doscopic thyroidectomy through oral vestibular approach has better aesthetic appearance,while endoscopic thyroidectomy through submental approach has lower pain and shorter operation time.

Thyroid papillary carcinomaResearch on propensity score matchingSubmental approachOral vestib-ular approachThyroidectomy

廖子聪、徐飞、陈浩、吴泽升、梁文丰、章银蓉、冯秀丽、汤治平

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528400 广东中山,中山市博爱医院普外科

528400 广东中山,中山市博爱医院妇科

甲状腺微小乳头状癌 倾向性评分匹配研究 颏下入路 口腔前庭入路 甲状腺切除术

2024

转化医学杂志
海军总医院

转化医学杂志

CSTPCD
影响因子:0.671
ISSN:2095-3097
年,卷(期):2024.13(8)