摘要
俯卧位通气（PP）是治疗急性呼吸窘迫综合征（ARDS）重要的呼吸支持手段，现已有大量的临床研究表明：PP能改善ARDS患者的预后。PP能改善氧合、进而降低病死率，主要是由于俯卧位后能改善患者病变肺组织通气-血流比。电阻抗断层成像技术（EIT）的技术特点使其能对俯卧位患者进行床旁监测，可动态观察俯卧位时肺通气、肺血流灌注的变化，进而判断PP的效果，从而指导临床治疗。本文通过对EIT技术以及临床应用，尤其是其在PP中的应用研究进行综述，旨在提高对EIT监测技术的认识，更好地理解PP改善氧合的呼吸生理学机制，促进EIT技术在PP中更高效精准的应用。
Abstract
Prone positioning (PP) is an important means of respiratory support in the treatment of acute respiratory distress syndrome (ARDS). The prognosis of ARDS patients can be improved by PP according to a large number of clinical trials. PP can increase oxygenation, thereby reducing mortality, which resulted in improved ventilation-perfusion matching and oxygenation. Electrical impedance tomography (EIT) can provide real-time visualization of lung ventilation in patients at the bedside. EIT is an ideal tool for the dynamic assessment of pulmonary physiological changes, especially for regional ventilation-perfusion matching and ventilation, so as to guide clinical treatment. The purpose of this article is to improve the understanding of EIT and the respiratory physiological mechanisms of PP in improving oxygenation. Accordingly it will facilitate the more efficient and accurate application of EIT in PP.
基金项目
上海申康医院发展中心临床三年行动计划资助项目(SHDC2020CR2013A)
上海申康医院发展中心临床三年行动计划资助项目(SHDC2020CR5010-003)
万方数据