摘要
液体管理是危重症患者管理的重要环节之一，液体过负荷状态对危重症患者的预后产生不良影响。目前超滤已广泛用于危重症患者的液体清除治疗，研究表明净超滤率与危重症患者预后相关，然而可以改善预后的最佳净超滤率仍未达成共识。本文将连续性肾脏替代治疗（CRRT）超滤应用现状及其对危重症患者预后的影响作一综述，为重症医师明确超滤概念，应用超滤进行容量管理提供参考，以更充分发挥CRRT治疗效果，防止超滤设定不合理对患者产生不良影响。
Abstract
Fluid management is one of the key components of the management of critically ill patients. Fluid overload in critically ill patients has a strong adverse impact on prognosis. Nowadays, ultrafiltration has been used for fluid removal in critically ill patients. Studies have shown that the net ultrafiltration rate is related to the prognosis of critically ill patients, however, there is still no consensus on the best net ultrafiltration rate. This article focuses on the concept and mechanism of ultrafiltration, the application of ultrafiltration for volume management, the relationship between net ultrafiltration rate and prognosis, and the application of ultrafiltration in different diseases.
基金项目
北京市属医院科研培育计划项目(PX2021003)
万方数据