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中医药治疗薄型子宫内膜的研究进展

Research Progress in the Treatment of Thin Endometrium with Traditional Chinese Medicine

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子宫内膜薄是引起月经过少、反复流产、不孕等疾病的重要原因之一,该疾病治疗困难且早期不易发现.该文通过回顾近年来研究文献发现,中医药治疗薄型子宫内膜(thin endometrium,TE)临床疗效佳、副作用少,其不仅能直接作用于子宫内膜促进相关因子的表达、抑制炎症因子、调节体内雌激素水平、促进细胞增殖或凋亡、增加内膜容受性,并且还能调控多种信号通路,多靶点、全方面的治疗TE.目前临床研究表明,单纯内服中药、单纯外治法、中医内外联合及中西医结合等治疗方式能够有效治疗薄型子宫内膜,改善患者的临床症状.
Thin endometrium is one of the important causes of menorrhagia,recurrent abortion,infertility and other diseases,which is difficult to treat and difficult to detect in the early stage.By reviewing the research literature in recent years,the author found that traditional Chinese medicine has good clinical efficacy and few side effects in the treatment of thin endometrium.It can not only directly promote the expression of related factors,inhibit inflammatory factors,regulate the level of estrogen in the body,promote cell proliferation or apoptosis,increase endometrial receptivity,but also regulate a variety of signal pathways,multi-target,all-round treatment of TE.The current clinical research shows that simple internal administration of traditional Chinese medicine,simple external treatment,internal and external combination of traditional Chinese medicine and the combination of traditional Chinese and western medicine can effectively treat thin endometrium and improve the clinical symptoms of patients.

thin endometriumtraditional Chinese medicinemechanism researchsignal pathway

李娜、赵翠英

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河北北方学院,张家口,075000,中国

廊坊市中医医院,廊坊,065000,中国

薄型子宫内膜 中医药 机制研究 信号通路

廊坊市科学技术研究与发展计划自筹经费项目

2023013058

2024

神经药理学报
河北北方学院 中国药理学会

神经药理学报

影响因子:0.283
ISSN:2095-1396
年,卷(期):2024.14(4)