Evaluation of inactivation effect of commercial disinfectant on African swine fever virus based on model virus
In order to evaluate and prove the elimination effect of commercial disinfectants on African swine fever virus(ASFV),and to provide reference for the screening of disinfectants.In this study,the similarity of physicochemical characteristics of pseudorabies virus(PRV)and ASFV virus was used to establish a disinfectant cell evaluation model with PRVas an alternative marker strain.The inactivation effect of three commercially available disinfectants on PRV grown in HBK-21 cells was tested in vitro.The disinfecting effect of the three disinfectants was evaluated from several aspects on the antiviral effect of the three disinfectants.The results showed that glutaraldehyde methyl bromide solution with an effective content of 0.125 g·L-1,peracetic acid solution with an effective content of 0.5 g·L-1 and sodium dichloroisocyanurate could effectively inactivate PRV at room temperature for 30 min.Among them,peracetic acid comprehensive evaluation is the best;Glutaraldehyde decyl methyl bromide is the most cost-effective,but it requires a long time of elimination and is seriously affected by low temperature.This study can provide theoretical basis for disinfectant screening for the prevention and control of ASFV infection in livestock farms,and provide reference for the establishment of disinfection standards for ASFV.
万方数据
维普
