Drug coated balloons and drug-eluting stents for the treatment of coronary small vessel stenosis with mild calcification comparison of efficacy and safety
Objective To compare the efficacy and safety of drug coated balloon(DCB)and drug eluting stent(DES)in the treatment of coronary small vessel stenosis with mild calcification.Method Eighty patients with coronary small ves-sel stenosis and mild calcification admitted to Haiyan County People's Hospital in Zhejiang Province from August 2020 to October 2022 were randomly divided into a stent group(drug-eluting stent treatment)and a balloon group(drug-coated bal-loon treatment),with 40 cases in each group.Record the minimum lumen diameter of two groups before surgery,after surgery,and 1 year after surgery,and calculate the late stage lumen loss and net increase in lumen diameter 1 year after surgery.Statistically analyze the rates of target vessel restenosis and adverse events such as myocardial infarction,all-cause mortality,cerebrovascular accidents,and target vessel reconstruction within one year after surgery in two groups.Results There was no statistically significant difference in the minimum lumen diameter between the two groups before,after,and 1 year after surgery(P＞0.05).However,compared with before treatment,the minimum lumen diameter increased after surgery and 1 year after surgery(P＜0.05);There was no statistically significant difference(P＞0.05)between the two balloon groups in terms of late stage luminal loss and net increase in luminal diameter at 1 year after surgery.After 1 year of surgery.there was no statistically significant difference in the rate of target vessel restenosis between the two groups(5.00％&7.50％)(x2=0.213,P=0.644).However,at 6 months and 1 year after surgery,there was no statistically significant difference in the inci-dence of adverse events such as myocardial infarction,all-cause death,cerebrovascular accidents,and target vessel recon-struction between the two groups(P＞0.05).Conclusion Drug coated balloons used for coronary small vessel stenosis with mild calcification can achieve the same efficacy and safety as drug-eluting stents,and can be used as an alternative treat-ment option for drug-eluting stents in clinical practice.
coronary small vessel stenosismild calcificationdrug coated balloondrug eluting stenttherapeutic ef-fectsecurity
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