Prediction value of hypersensitive C-reactive protein to albumin ratio in in-stent restenosis after percutaneous coronary inter-vention
Objective To investigate the predictive value and clinical significance of ratio of high sensitivity C-reactive protein(hs-CRP)to albumin(ALB)(hs-CRP/ALB)in in-stent restenosis(ISR).Methods A retrospective analysis was performed on 187 patients with coronary heart disease who received stent implantation in Zhejiang Greentown Cardiovascular Hospital from January 2019 to January 2022.Coronary angiography(CAG)was performed again 6 months to 1 years after the operation.Patients were divided into an ISR group(30 cases)and a non-ISR group(157 cases)according to the presence or absence of ISR.Univariate and multivariate logistic regression were used to analyze factors correlated with ISR after percutaneous coronary intervention(PCI),and ROC curve was used to analyze the predictive value of hs-CRP/ALB,neutrophil to lymphocyte ratio(NLR),and stent length on ISR after PCI.Results Before operation,hs-CRP/ALB,NLR and stent length in the ISR group were all significantly higher or larger than those of the control group(all P＜0.05),and they were independent risk factors for coronary ISR.The ROC curve showed that the AUC of hs-CRP/ALB,NLR and stent length in predicting ISR risk were 0.755,0.605,and 0.626,respectively,with the cut-off values of respective 0.249,2.069,and 24,the sensitivity of respective 63.33％,80.00％,and 63.33％,and the specificity of 88.54％,45.22％,and 57.32％,respectively.Conclusion Hs-CRP/ALB,NLR and stent length are associated with ISR in patients with coronary heart disease,and are expected to be potential prodictors.
Percutaneous coronary interventionIn-stent restenosisHypersensitive C-reactive protein to albumin ratioNeutrophil to lymphocyte ratio
万方数据
维普
