Analysis on clinical features and prognostic factors of cancer-related ischemic stroke
Objective To analyze the clinical features of cancer-related ischemic stroke and the factors affecting its prognosis.Methods A total of 94 patients with cancer-related ischemic stroke who were admitted to Shaoxing Second Hospital Medical Community General Hospital from January 2018 to June 2022 were selected.According to the distribution pattern of hyperintense lesions by diffusion-weighted imaging(DWI),the patients were divided into one territory group,two territories group and three territories group,and the general clinical data and imaging characteristics of the three groups were analyzed,as well as the relationship between different territory signs and cerebral small vessel disease burden.The modified Rankin scale(mRS)was used to evaluate the prognosis at 90 days post-discharge.Patients with scores of 0-2 points were assigned to the good prognosis group,and those with scores over 2 points were assigned to the poor prognosis group.The general data,imaging characteristics,and factors affecting the prognosis of the two groups were analyzed.Results Creatinine,D-dimer and cerebral small vessel disease burden in the three groups were significantly different(all P＜0.05).Cerebral small vessel disease burden was an influencing factor of the territory signs of cancer-related ischemic stroke(P＜0.05).Creatinine,D-dimer and cerebral small vessel disease burden in the good prognosis group were lower than those of the poor prognosis group,and the difference was statistically significant(all P＜0.05).D-dimer and cerebral small vessel disease burden were factors affecting the prognosis of cancer-related ischemic stroke(both P＜0.05).Conclusion The distribution pattern of DWI lesions in cancer-related ischemic stroke is related to cerebral small vessel disease burden.D-dimer and cerebral small vessel disease burden are prognostic factors for cancer-related ischemic stroke,which should be paid close attention to.
CancerIschemic strokeCerebral small vessel diseasePrognosis
万方数据
维普
