Effect of sodium hyaluronate gel combined with estradiol/estradiol dydrogesterone tablets on the prevention of intrauterine adhesion and menstrual recovery after induced abortion
Objective To analyze the effect of sodium hyaluronate gel combined with estradiol/estradiol dydrogesterone(Femoston)tablets on the prevention of intrauterine adhesion and menstrual recovery after induced abortion.Methods A total of 286 patients who underwent induced abortion in Lishui Hospital of Traditional Chinese Medicine from June 2019 to October 2022 were enrolled in the study.Patients were randomly divided into two groups with 143 patients in each group.The control group was treated with Femoston tablets,and the study group was treated with sodium hyaluronate gel combined with Femoston.Postoperative recovery,intrauterine adhesion,first menstruation,menstruation during follow-up and the incidence of complications were compared between the two groups.Results The duration of abdominal pain and vaginal bleeding in the study group were shorter than those in the control group,the volume of vaginal bleeding was less than that in the control group,and the endometrial thickness was higher than those in the control group(all P＜0.01).The total incidence of postoperative intrauterine adhesion in the study group was lower than that in the control group(4.90％vs.12.59％,P=0.021).The time of menstruation recovery in the study group was shorter than that in the control group,the menstrual period was longer than that in the control group,and the menstrual volume was more than that in the control group(all P＜0.01).During the postoperative follow-up period,the average menstrual cycle of the patients in the study group was shorter than that in the control group,the average menstrual duration was longer than that in the control group,and the average menstrual volume was more than that of the control group(all P＜0.01).The incidence rate of postoperative complications in the study group was lower than that in the control group(3.50％vs.10.50％,P=0.020).Conclusion Sodium hyaluronate gel combined with Femoston tablets can promote endometrial repair and menstruation recovery after induced abortion with lower incidence of postoperative complications.
万方数据
维普
