首页|乳腺乳头状癌的临床病理及影像学特征分析

乳腺乳头状癌的临床病理及影像学特征分析

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目的 分析乳腺乳头状癌各亚型的临床病理学和影像学特征.方法 回顾性分析2015年1月至2022年6月浙江大学医学院附属第二医院经手术切除治疗及病理检查证实为乳腺乳头状癌的82例患者,根据病理结果,分为导管内乳头状癌(pDCIS)组23例,包裹性乳头状癌(EPC)组10例,实性乳头状癌(SPC)组13例,浸润性乳头状癌组24例,乳头状癌伴其他成分(混合型)组12例,对各组临床病理和影像学特征进行比较分析.结果 SPC组及pDCIS组多表现为乳头溢液或溢血(P=0.013),EPC组在超声下典型特征是囊实性界清肿块(P=0.002),SPC组增强MRI下多呈区域强化(P=0.012),乳腺乳头状癌易被乳腺X线检查漏诊.结论 超声联合增强MRI有助于乳腺乳头状癌检出和亚型鉴别.囊实性肿块是EPC特征性影像学表现,提高对不同亚型的认识有助于临床鉴别诊断.
Clinicopathologic and imaging characteristics of papillary carcinoma of the breast
Objective To explore the clinicopathologic and imaging characteristics of subtypes of breast papillary carcinoma.Methods Eighty two patients with pathological diagnosis of breast papillary carcinoma in the Second Affiliated Hospital of Zhejiang University School of Medicine from January 2015 to June 2022 were enrolled.The patients were classified into the following groups based on pathology:25 cases of pDCIS,10 cases of EPC,13 cases of SPC,24 cases of invasive papillary carcinoma and 12 cases of mixed type,the clinicopathological and imaging features were compared.Results Solid papillary carcinoma(SPC)and intraductal papillary carcinoma(pDCIS)showed higher percentage of nipple discharge than other subgroups(P=0.013).Encapsulated papillary carcinoma(EPC)was characterized by a well-circumstanced mass with cystic/solid echopattern on breast ultrasound(US)(P=0.002).SPC was likely to show regional enhancement on magnetic resonance imaging(MRI)(P=0.012).It was difficult to differentiate papillary tumors by mammography(MG).Conclusion US combined with MRI helps to differentiate subtype of breast papillary carcinoma.The cystic-solid mass is a characteristic imaging feature of EPC,and increasing awareness of different subtypes contributes to clinical differential diagnosis.

Breast papillary carcinomaClinicopathologic featuresImaging characteristicsEncapsulated papillary carcinoma

叶欣、黄建

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310058 杭州,浙江大学医学院

浙江大学医学院附属第二医院乳腺外科

乳腺乳头状癌 临床病理特征 影像学特征 包裹性乳头状癌

希斯科-朝阳肿瘤研究基金

Y-Young2023-0193

2024

浙江医学
浙江省医学会

浙江医学

CSTPCD
影响因子:0.428
ISSN:1006-2785
年,卷(期):2024.46(8)
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