Clinicopathologic and imaging characteristics of papillary carcinoma of the breast
Objective To explore the clinicopathologic and imaging characteristics of subtypes of breast papillary carcinoma.Methods Eighty two patients with pathological diagnosis of breast papillary carcinoma in the Second Affiliated Hospital of Zhejiang University School of Medicine from January 2015 to June 2022 were enrolled.The patients were classified into the following groups based on pathology:25 cases of pDCIS,10 cases of EPC,13 cases of SPC,24 cases of invasive papillary carcinoma and 12 cases of mixed type,the clinicopathological and imaging features were compared.Results Solid papillary carcinoma(SPC)and intraductal papillary carcinoma(pDCIS)showed higher percentage of nipple discharge than other subgroups(P=0.013).Encapsulated papillary carcinoma(EPC)was characterized by a well-circumstanced mass with cystic/solid echopattern on breast ultrasound(US)(P=0.002).SPC was likely to show regional enhancement on magnetic resonance imaging(MRI)(P=0.012).It was difficult to differentiate papillary tumors by mammography(MG).Conclusion US combined with MRI helps to differentiate subtype of breast papillary carcinoma.The cystic-solid mass is a characteristic imaging feature of EPC,and increasing awareness of different subtypes contributes to clinical differential diagnosis.
Breast papillary carcinomaClinicopathologic featuresImaging characteristicsEncapsulated papillary carcinoma