Risk factors of pathological underestimation in breast non-mass lesions by core needle biopsy
Objective To explore the risk factors of pathological underestimation in breast non-mass lesion(NML)by ultrasound-guided core needle biopsy(US-CNB).Methods A total of 239 patients with breast NML underwent US-CNB in Yongkang First People's Hospital from March 2018 to December 2021.The clinical manifestations,ultrasonic characteristics,puncture related parameters and pathological results of patients were retrospectively analyzed.Comparing the US-CNB pathological results with postoperative pathological results,patients were divided into underestimated group and non-underestimated group.The risk factors of pathological underestimation were analyzed.Results According to US-CNB results,there were 84 cases of benign lesions,16 cased of high-risk lesions,64 cases of carcinoma in situ and 75 cases of invasive carcinoma.The postoperative pathology showed that 28 cases were pathologically underestimated(11.72％).Univariate analysis showed that there were significant differences between the underestimated group and the non-underestimated group in NML local pain,ultrasound type,microcalcification,blood flow grade,grade of breast imaging reporting and data system(BI-RADS),multi-point sampling and axillary abnormal lymph nodes(all P＜0.05).Multivariate analysis showed that ultrasound type Ⅱ,color flow grade,multi-point sampling,and axillary abnormal lymph nodes were independent risk factors for the underestimation in NML by US-CNB(all P＜0.05).Conclusion There is a high pathological underestimation rate in breast non-mass lesions by US-CNB.Ultrasound type Ⅱ,high blood grade,insufficient multi-point sampling and axillary abnormal lymph nodes in NML are the main factors influencing the underestimation in NML by US-CNB.
万方数据
维普
