首页|超声引导下药物注射治疗膝关节炎的疗效及危险因素分析

超声引导下药物注射治疗膝关节炎的疗效及危险因素分析

扫码查看
目的 分析超声引导下药物注射治疗膝关节炎的疗效及危险因素.方法 选取2023年10月至2024年3月中国人民解放军63680部队医院收治的80例经超声引导下药物注射治疗膝关节炎患者.根据患者预后分为治愈组(61例)和未治愈组(19例),比较两组患者的临床资料,采用多因素logistic回归分析影响疗效的危险因素;绘制ROC图,评估各项临床指标预测疗效的效能.结果 两组患者年龄、病程、BMI、高尿酸、膝关节手术史、创伤史、CRP、IL-6、WBC、膝关节Lysholm评分比较,差异均有统计学意义(均P<0.05);多因素logistic回归分析结果显示,年龄、BMI、病程、CRP、IL-6、WBC是影响疗效的独立危险因素(OR=1.151、1.220、4.354、1.635、1.056、1.330,均P<0.05),其中病程是影响疗效的强相关因素.ROC曲线显示,CRP预测疗效的效能较高(AUC=0.801),灵敏度为0.842,特异度为0.864.结论 年龄、BMI、病程、CRP、IL-6、WBC是影响超声引导下药物注射治疗膝关节炎疗效的独立危险因素,其中病程与疗效强相关;CRP能较好评估超声引导下药物注射治疗膝关节炎的疗效.
Efficacy and risk factors of ultrasound-guided drug injection in the treatment of knee osteoarthritis
Objective To analyze the efficacy and risk factors of ultrasound-guided drug injection in the treatment of knee osteoarthritis.Methods From October 2023 to March 2024,80 patients with knee osteoarthritis treated with ultrasound-guided drug injection were selected from Chinese People's Liberation Army 63680 Unit Hospital.Comparative analysis was conducted on the clinical data of patients who were divided into a cured group(61 cases)and an uncured group(19 cases)after recovery.Univariate and multivariate logistic regression analyses were used to identify the risk factors affecting treatment efficacy;An ROC chart was drawn to evaluate the clinical indicators that predict efficacy.Results There were statistically significant differences in age,course of disease,BMI,hyperuricemia,knee surgery history,trauma history,CRP,IL-6,WBC,and knee Lysholm scores between the two groups of patients(all P<0.05);The results of multivariate logistic analysis showed that age,BMI,course of disease,CRP,IL-6,and WBC were independent risk factors affecting treatment efficacy(OR=1.151,1.220,4.354,1.635,1.056,1.330,all P<0.05).Among the independent risk factors,course of disease showed the highest OR than other risk factors,and it was strongly correlated with the treatment efficacy.ROC curve showed that CRP had the best predictive efficacy in predicting curative effect(AUC=0.801),with higher sensitivity(0.842)and specificity(0.864)than other clinical indicators(all P<0.05).Conclusion Age,BMI,course of disease,CRP,IL-6,and WBC are independent risk factors that affect the efficacy of ultrasound-guided drug injection therapy in the treatment of knee osteoarthritis,among which,course of disease is strongly associated with efficacy.CRP can accurately evaluate the efficacy of ultrasound-guided drug injection therapy in the treatment of knee arthritis.

Ultrasound guidanceKnee arthritisTherapeutic effectRisk factor

杨灵杰、徐秋琴、孙国祥、贺奇志、郭万亮

展开 >

214400 无锡,中国人民解放军63680部队医院超声科

苏州大学

苏州大学附属儿童医院超声科

214400 无锡,中国人民解放军63680部队医院疼痛科

苏州大学附属儿童医院放射科

展开 >

超声引导 膝关节炎 疗效 危险因素

2024

浙江医学
浙江省医学会

浙江医学

CSTPCD
影响因子:0.428
ISSN:1006-2785
年,卷(期):2024.46(9)