Risk factors analysis and nursing strategies for pulmonary infection in premature infants with patent ductus arteriosus
Objective To analyze the risk factors for pulmonary infection in preterm infants with patent ductus arteriosus(PDA)so as to provide a basis for the prevention strategies.Methods Data of 144 premature delivery children with PDA admitted to the Children's Hospital Affiliated to Zhejiang University School of Medicine from July 2018 to December 2020 were collected.They were divided into an infected group(85 cases)and a non infected group(59 cases)based on the occurrence of pulmonary infection.Univariate analysis was performed on data of the two groups,and statistically significant factors were included in logistic regression analysis for independent risk factors.Results Among 144 premature delivery cases with PDA,85 cases were complicated with pulmonary infection,with an infection rate of 59.03％.A total of 96 infected strains were isolated,including 72 Gram negative bacteria,mainly Klebsiella pneumoniae,and 24 strains of Gram positive bacteria,mainly Staphylococcus aureus.Multivariate logistic regression analysis found that more than 2 tracheal intubations,had hypoproteinemia,PDA diameter greater than 3 mm,gestational age less than 28 weeks,had peripherally inserted central venous catheters were independent risk factors for pulmonary infection in PDA premature infants(all P＜0.05).Conclusion The occurrence of pulmonary infection in premature infants with PDA is the result of a combined actions of multiple factors.Not only these factors but also their combined effects should be considered to provide comprehensive prevention and treatment strategies for pulmonary infection.
万方数据
维普
