Efficacy and safety of two percutaneous mechanical thrombectomy methods in the treatment of acute lower limb ischemia
Objective To compare the clinical efficacy and safety of two percutaneous mechanical thrombectomy methods(Rotarex vs.Angiojet)in the treatment of acute lower limb ischemia(ALLI).Methods Retrospective analysis was conducted on 98 patients treated with ALLI using Rotarex or Angiojet in the Department of Vascular Surgery,Taizhou Hospital,Zhejiang Province from February 2020 to February 2023.Among which,38 patients received mechanical thrombectomy(Rotarex group)and 60 patients received mechanical thrombus aspiration(Angiojet group).The baseline data of the two groups were collected,and the clinical efficacy indexes such as the success rate of surgical techniques and the safety evaluation indexes such as complications were compared between the two groups.Results There were no significant differences in baseline data including the cause and degree of ischemia and time of onset between the two groups(all P＞0.05).The technical success rate was 100.00％in the Rotarex group and 98.33％in the Angiojet group.In the Rotarex group,residual stenosis[(46.18±12.97)％vs.(54.25±14.67)％],stent implantation rate(47.37％vs.73.33％),ankle-brachial index(ABI)improvement value[(0.67±0.10)vs.(0.63±0.11)],and postoperative hospital stay[5(3,6)d vs.7(5.5,8.5)d]were better than those of the Angiojet group(all P＜0.05).There were no significant differences in improvement of ischemic symptoms,and amputation and reoperation rate within 30 days between the two groups(all P＞0.05).Compared with preoperative results,postoperative WBC,neutrophil/lymphocyte count ratio and CRP in Angiojet group were increased(all P＜0.05),while Hb was decreased(P＜0.05).The two groups showed no significant differences in perioperative liver and kidney functions,Fib,D-dimer and incidence of complications(all P＞0.05).Conclusion Both Rotarex and Angiojet techniques have good efficacy and safety for acute lower limb ischemia,but Rotarex system is more superior in efficacy,and thrombectomy efficiency with less impacts on the internal environment and higher safety.
万方数据
维普
