Value of texture analysis based on MRI T2WI and ADC images in differentiating T3 substage of rectal cancer
Objective To investigate the value of texture analysis based on MRI T2WI and apparent diffusion coefficient(ADC)images in differentiating T3 substages of rectal cancer.Methods Clinical and imaging data of 109 patients with pathologically confirmed rectal cancer admitted in Huangshan Shoukang Hospital and Changshu First People's Hospital from July 2016 to September 2020 were analyzed retrospectively.All patients underwent MRI examination,the contour of tumor was drawn on T2WI and ADC images,first-order texture features(mean value,standard deviation,P5,P10,P90,skewness,kurtosis and uniformity)and second-order texture features(energy,entropy,inertia and correlation)were measured.The differences in first-and second-order texture features between T3a and T3b_c stage were compared.The value of texture features for differentiating between T3a and T3b_c stage of rectal cancer was analyzed by ROC curve.Results There were 53 cases of T3a stage,42 cases of T3b stage,and 14 cases of T3c stage.On T2WI images,the kurtosis in patients with T3a stage was significantly lower than that in T3b_c stage,while uniformity and energy were significantly higher than those in T3b-c stage(all P＜0.05).The AUC of kurtosis,uniformity and energy in differentiating T3a and T3b-c stage was 0.668,0.638 and 0.806,respectively.On ADC images,skewness and entropy in T3a stage were significantly lower than those in T3b-c stage(all P＜0.05).The AUC of skewness and entropy in differentiating T3a and T3b_c stage was 0.626 and 0.731,respectively.Conclusion The texture analysis based on MRI T2WI and ADC images is useful in differentiating T3aand T3b_c stage of rectal cancer,and the diagnostic efficacy of energy based on T2WI images is the highest.
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