Efficacy and cost-effective comparisons between two types of endoscopic submucosal dissection in the treatment of colonic neoplasm with a diameter ≥ 20 mm
Objective To compare the efficacy and cost-effectiveness of hybrid endoscopic submucosal dissection(H-ESD)with conventional endoscopic submucosal dissection(C-ESD)for treating colonic neoplasms with a diameter ≥20 mm.Methods A retrospective analysis was conducted on the clinical data of patients with colonic neoplasm ≥20 mm in diameter who underwent H-ESD(71 cases)and C-ESD(85 cases),respectively,at the First Affiliated Hospital of Zhejiang University School of Medicine from January 2011 to December 2019.The general information and clinicopathological characteristics,as well as the curative effect,complications,recurrence,and cost-effectiveness,were compared between the two groups.Results There were no significant differences in gender,age,tumor location,preoperative biopsy pathological type,preoperative diagnosis,postoperative biopsy pathological type,tumor origin level,and follow-up examination methods between H-ESD and C-ESD groups(all P＞0.05).The maximum diameter and surface area of colonic tumors in H-ESD group were smaller than those of C-ESD group(both P＜0.05).There were no statistically significant differences in the curative effect,complications,and recurrence,as well as operation time,surgical equipment costs,and hospital stay between H-ESD and C-ESD groups(all P＞0.05).However,the total cost of H-ESD group was lower than that of C-ESD group(P＜0.05),indicating that H-ESD is more cost-effective than C-ESD.Conclusion H-ESD and C-ESD are similar in safety and effectiveness while treating colonic tumors with a diameter ≥20 mm.However,compared to C-ESD,H-ESD is more cost-effective with a lower total cost,thus deserving clinical promotion.
万方数据
维普
