Effects of focal solution short-course treatment plus escitalopram on negative mood and cognitive function for adolescent pa-tients with depression
Objective To investigate the effects of focused solution short-course therapy plus escitalopram on negative mood and cognitive function in adolescent patients with depression.Methods Sixty adolescent patients with depression who attended the Hangzhou Seventh People's Hospital from December 2021 to June 2023 were randomly divided into the study group and the control group with 30 cases in each group.The control group was treated with escitalopram alone,and the study group received focal solution short-course treatment plus escitalopram.The clinical efficacy,negative mood,cognitive function,and adverse reactions of the two groups were compared.Results Patient health questionnaire(PHQ-9)scores decreased in both groups from 2 to 6 weeks after treatment,and the PHQ-9 scores were better in the study group than those in the control group(all P＜0.05).Hamilton depression scale(HAMD)scores and generalized anxiety self-Rating Scale(GAD-7)scores were reduced in both groups from 2 to 6 weeks after treatment,and GAD-7 scores were lower in the study group than those in the control group(all P＜0.05).The mental state measurement scale(MMSE)scores increased in both groups from 2 to 6 weeks after treatment,and the MMSE scores in the study group were better than those in the control group(all P＜0.05).The total incidence of adverse reactions was lower in the study group compared with the control group(P＜0.05).Conclusion The focal solution short-course treatment plus escitalopram can relieve anxiety and negative emotion,improve cognitive function and reduces the incidence of adverse effects in adolescent depression patients,which is worthy of promoting in clinic application.
万方数据
维普
