Application of preoperative CT-guided indocyanine green localization in thoracoscopic resection of sub centimeter ground glass nodules in the lungs
Objective To explore the safety and clinical efficacy of CT-guided intrapulmonary injection of indocyanine green(ICG)with fluorescence staining localization in thoracoscopic resection of sub centimeter ground glass nodules(GGN)in the lungs.Methods The clinical data of 139 patients who underwent video-assisted thoracoscopic surgery(VATS)to remove sub centimeter pulmonary ground glass nodules in the Department of Thoracic Surgery of the First Affiliated Hospital of Ningbo University from January to May 2022 were retrospectively analyzed,and divided into the observation group and the control group according to different positioning methods.In the observation group,GGN of the 81 patients were removed after being positioned by preoperative CT-guided ICG injection in the lungs,while in the control group,GGN of the 58 patients were resected based on anatomical location.The perioperative and pathological data of the two groups were compared,and the recurrence of lung GGN was evaluated after one year postoperative follow-up.Results The success rate of preoperative localization was 98.77％in the observation group and 94.83％in the control group,with no statistical significance(P＞0.05).There were statistically significant differences in pulmonary tissue resection method,operation time,intraoperative blood loss,postoperative drainage volume,chest tube retention time,postoperative hospital stay and postoperative complications between the two groups(all P＜0.05).No significant difference was observed in pathological results and the number of lymph node dissection between the two groups(both P＞0.05).After one year follow-up,there was no significant difference in recurrence rate between the two groups(P＞0.05).Conclusion Compared with traditional ananatomical positioning,preoperative CT-guided intrapulmonary injection of ICG for positioning is helpful for rapid thoracoscopic resection of sub centimeter lung GGN,with short recovery time postoperatively,high safety,and no increase in recurrence rate.The efficacy is reliable and worthy of clinical promotion and application.
国家科技期刊平台
NSTL
万方数据
