Influencing factors of failed oxygen therapy weaning in patients with supratentorial deep tumor after general anesthesia
Objective To explore the influencing factors of failed oxygen therapy weaning in patients with supratentorial deep tumor after general anesthesia,and construct a nomogram prediction model.Methods Clinical data of 364 patients with supratentorial deep tumor undergoing surgical resection under general anesthesia from January 2016 to December 2021 in the First Affiliated Hospital of Wenzhou Medical University were retrospectively analyzed,including 105 cases who failed oxygen therapy weaning after general anesthesia and 259 cases with successful weaning.Study subjects were randomly divided into training set(n=291)and validation set(n=73)(8∶2).Univariate and multivariate logistic regression was using to analysis the influencing factors for failed weaning from supplemental oxygen therapy after general anesthesia.Results Multivariate logistic regression analysis showed that age,BMI,dezocine,transfusion and anesthesiologist handovers during operation were independent predictors of failed weaning from supplemental oxygen therapy(all P＜0.05).Based on the risk factors,a nomogram prediction model was developed,the AUC of the model in the validation set was 0.831,the sensitivity and specificity was 0.946 and 0.444.Conclusion The nomogram model based on logistic regression analysis has good predictive ability,which may be used to predict and prevent failed weaning from supplemental oxygen therapy after general anesthesia in patients undergoing supratentorial deep tumor resection.
Supratentorial deep tumorHypoxemiaInfluence factorsNomogram
万方数据
维普
