首页|复苏周期单囊胚移植临床结局影响因素修正Poisson分析:一项回顾性队列研究

复苏周期单囊胚移植临床结局影响因素修正Poisson分析:一项回顾性队列研究

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目的 分析复苏周期单囊胚移植临床结局的影响因素.方法 回顾性分析2017年1月至2022年12月在湖州市妇幼保健院生殖中心接受复苏周期单囊胚移植的不孕患者的618个复苏周期,根据囊胚移植后是否临床妊娠分为妊娠组300个和未妊娠组318个,根据囊胚移植后是否活产分为活产组241个和未活产组377个.采用单因素和修正Poisson分析影响复苏周期单囊胚移植临床妊娠、活产的因素.结果 妊娠组和未妊娠组患者年龄、双卵巢窦卵泡数(AFC)、血清抗米勒管激素(AMH)水平、移植周期数、囊胚天数、胚胎类型比较差异均有统计学意义(均P<0.05).修正Poisson分析显示患者年龄、移植周期数、囊胚天数均是影响临床妊娠的重要因素(均P<0.05).活产组和未活产组患者年龄、AFC、AMH、BMI、移植周期数、囊胚天数、胚胎类型比较差异均有统计学意义(均P<0.05).修正Poisson分析显示患者年龄、囊胚天数是影响活产的重要因素(均P<0.05).结论 患者年龄、囊胚发育天数是影响复苏周期单囊胚移植临床妊娠和活产的重要因素.
Analysis on the influencing factors for clinical outcomes of single blastocyst transfer during resuscitation cycles through adjust-ed Poisson regression:a retrospective cohort study
Objective To analyze the influencing factors for clinical outcomes of single blastocyst transfer during resuscitation cycles.Methods A retrospective analysis was conducted on 618 resuscitation cycles of infertile patients who received single blastocyst transfer during resuscitation cycles at the Reproductive Center of Huzhou Maternal and Child Health Health Hospital from January 2017 to December 2022.The patients were divided into clinical pregnancy group(n=300)and non-pregnancy group(n=318)according to whether they obtained clinical pregnancy after transferring blastocyst,and they were also divided into live birth group(n=241)and non-live birth group(n=377)according to whether they obtained live birth after transferring blastocyst.The factors affecting the clinical pregnancy and live birth were analyzed by univariate analysis and adjusted Poisson regression.Results The differences in age,antral follicle count(AFC),serum anti-Mullerian hormone(AMH)level,number of transfer cycles,the development days of the blastocyst,and blastocyst type were statistically significant between the clinical pregnancy group and the non-pregnancy group(all P<0.05).Adjusted Poisson regression showed that age,number of transfer cycles,and the development days of the blastocyst were the most important factors influencing the clinical pregnancy(all P<0.05).The differences in age,AFC,serum AMH level,BMI,number of transfer cycles,the development days of the blastocyst,and blastocyst type were statistically significant between the live birth group and the non-live birth group(all P<0.05).Adjusted Poisson regression showed that age and the development days of the blastocyst were the most important factors influencing the live birth(both P<0.05).Conclusion The patient's age and the development days of the blastocyst are important factors influencing the clinical pregnancy and live birth of single blastocyst transfer during resuscitation cycles.

Retrospective studyResuscitation cyclesSingle blastocyst transferClinical pregnancyLive birth

潘晓琴、沈丽雯、周媛萍

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313000 湖州市妇幼保健院生殖中心

回顾性研究 复苏周期 单囊胚移植 临床妊娠 活产

湖州市公益性应用研究项目

2023GYB08

2024

浙江医学
浙江省医学会

浙江医学

CSTPCD
影响因子:0.428
ISSN:1006-2785
年,卷(期):2024.46(17)
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