Analysis on the influencing factors for clinical outcomes of single blastocyst transfer during resuscitation cycles through adjust-ed Poisson regression:a retrospective cohort study
Objective To analyze the influencing factors for clinical outcomes of single blastocyst transfer during resuscitation cycles.Methods A retrospective analysis was conducted on 618 resuscitation cycles of infertile patients who received single blastocyst transfer during resuscitation cycles at the Reproductive Center of Huzhou Maternal and Child Health Health Hospital from January 2017 to December 2022.The patients were divided into clinical pregnancy group(n=300)and non-pregnancy group(n=318)according to whether they obtained clinical pregnancy after transferring blastocyst,and they were also divided into live birth group(n=241)and non-live birth group(n=377)according to whether they obtained live birth after transferring blastocyst.The factors affecting the clinical pregnancy and live birth were analyzed by univariate analysis and adjusted Poisson regression.Results The differences in age,antral follicle count(AFC),serum anti-Mullerian hormone(AMH)level,number of transfer cycles,the development days of the blastocyst,and blastocyst type were statistically significant between the clinical pregnancy group and the non-pregnancy group(all P<0.05).Adjusted Poisson regression showed that age,number of transfer cycles,and the development days of the blastocyst were the most important factors influencing the clinical pregnancy(all P<0.05).The differences in age,AFC,serum AMH level,BMI,number of transfer cycles,the development days of the blastocyst,and blastocyst type were statistically significant between the live birth group and the non-live birth group(all P<0.05).Adjusted Poisson regression showed that age and the development days of the blastocyst were the most important factors influencing the live birth(both P<0.05).Conclusion The patient's age and the development days of the blastocyst are important factors influencing the clinical pregnancy and live birth of single blastocyst transfer during resuscitation cycles.