摘要
目的 分析基于倾向评分匹配的早期乳腺癌患者保乳术后大分割放疗与常规放疗住院天数和住院费用的差异.方法 回顾性选择2020年1月至2022年12月浙江省肿瘤医院放疗科收治的T1~4N0~3M0期早期乳腺癌患者612例,分为大分割组(127例)和常规组(485例).采用倾向评分匹配得到121对患者,对匹配成功的患者的住院天数和住院总费用及各住院分项费用进行分析.结果 常规组和大分割组的住院天数分别为7.00(5.00,8.00)d和6.00(5.00,7.00)d,住院费用分别为 35 509.47(33 379.65,37 247.48)元和 25 670.90(21 303.77,26 445.84)元,差异均有统计学意义(Z=-2.31、-5.06,均P<0.05).除康复类费用、中医类费用和血液和血液制品类费用外,大分割组的综合医疗服务费、诊断类费用、治疗类费用、中药类费用、耗材类费用和其他类费用的各分项费用均低于常规放疗组,差异均有统计学意义(均P<0.05).结论 大分割放疗能够减少乳腺癌患者的住院天数,降低住院费用,值得临床推广.
Abstract
Objective To compare the length of hospital stay and costs between hypofractionated and conventional radiotherapy modes for patients with breast cancer following breast-conserving surgery.Methods A total of 612 patients with breast cancer of pathological stages T1-4N0-3M0,who underwent breast-conserving surgery in Zhejiang Cancer Hospital from January 2020 to December 2022 were included in the study.Patients received radiotherapy following breast-conserving surgery,including 127 cases with hypofractionated radiotherapy and 485 cases with conventional radiotherapy.Using the propensity score matching method,121 pairs of patients were successfully matched.The length of hospital stay,total hospitalization costs,and various sub-item costs were compared between two groups.Results The median length of hospital stay for the conventional radiotherapy group was longer[7.00(5.00,8.00)d vs.6.00(5.00,7.00)d,P<0.05]and the total hospitalization costs were higher[35 509.47(33 379.65,37 247.48)yuan vs.25 670.90(21 303.77,26 445.84)yuan,P<0.05]than those for hypofractionated radiotherapy group.In addition,the sub-item costs of comprehensive medical services,diagnostic fees,treatment fees,traditional Chinese medicine fees,consumable fees,etc.in the hypofractionated radiotherapy group were lower than those in the conventional radiotherapy group(P<0.05).Conclusion Hypofractionated radiotherapy can shorten the postoperative radiotherapy course,reduce hospitalization time,and decrease treatment costs,thereby reducing hospitalization expenses of patients.