Application comparison between loach guide wire with bent head end and polytetrafluoroethylene-coated guide wire with J-shaped head end in transradial coronary angiography
Objective To evaluate and compare the effectiveness and safety of loach guide wire with bent head end and polytetrafluoroethylene (PTFE)-coated guide wire with J-shaped head end in coronary angiography (CAG) via the radial artery. Methods The study retrospectively selected 1695 patients with suspected coronary heart disease diagnosed at the First Affiliated Hospital of Ningbo University from April 2022 to April 2023. According to the guide wire type that patients used at the first time during CAG,patients were divided into a loach guidewire group with bent head (observation group,n=714) and a PTFE-coated guide wire group with J-shaped head end (control group,n=981). Patients in the two groups were compared in basic data,guide wire vascular passage rate,surgical time,radiation time,radiation dose,contrast dose,guide wire replacement ratio,left radial artery replacement ratio,contrast catheter replacement ratio,and surgical complications. The factors influencing the guide wire vessel passage rate were analyzed by multivariate logistic regression. Results The vascular passage rate of the observation group was higher than that of the control group (98.5% vs. 93.5%,P<0.05). The control group increased the vascular passage rate of the guide wire to 98.5% (966/981) by replacing the guide wire with a head-end bent loach guide wire. The observation group experienced shorter surgical time and radiation time,and lower radiation dose,contrast dose,wire replacement ratio,incidence of vascular spasm,and incidence of vagus reaction than the control group,and the differences were statistically significant (all P<0.05). There was no statistically significant difference in the proportion of vascular dissection,forearm hematoma,replacement of contrast catheter,and replacement of left radial artery between the two groups of patients (all P>0.05). Neither group of patients experienced vascular perforation or mediastinal hematoma. The results of multivariate logistic regression analysis revealed that both age and the first-time use of the loach guide wire with bent head end were influencing factors for the vascular passage rate of the guide wire (both P<0.05). Conclusion The loach guide wire with bent head end is more effective and safer than the PTFE-coated guide wire with J-shaped head end in transradial CAG surgery,which could be promoted in clinic.