首页|复方驱蚊精油化学成分分析及其驱避活性评价

复方驱蚊精油化学成分分析及其驱避活性评价

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[目的]分析由薄荷、浮萍、石菖蒲、迷迭香4种中药植物配伍而成的复方驱蚊精油的化学成分,并进行驱避活性评价.[方法]通过气质联用色谱技术(gas chromatography-mass spectrometer,GC-MS)分析复方驱蚊精油的化学成分,按照《空间驱避产品药效试验及评价(Y型管法)》,评价精油对白纹伊蚊成虫的驱避活性.[结果]鉴定出主要挥发性成分58种,占精油总成分的98.28％,萜类18种(44.99％)、烯烃类9种(20.27％)、酯类5种(14.07％)、芳香烃类8种(12.00％)、烷烃类7种(3.48％)、醇类9种(2.78％)、酮类2种(0.69％).复方驱蚊精油对白纹伊蚊的驱避率(percent repellency,PR)平均达90％.[结论]复方驱蚊精油的化学成分较多,对白纹伊蚊起到驱避作用的可能有薄荷醇、薄荷酮、α-蒎烯等多种化学成分,平均驱避效果达到A级水平.
Chemical Composition Analysis and Repellent Activity Evaluation of Compound Mosquito Repellent Essential Oil
[Objective]To analyze the chemical components of the compound essential oil for mosquito repellent,which was composed of Menthae haplocalyx Briq.,Spirodela polyrrhiza(L.)Schleid,Acorus tatarinowii Schott and Rosmarinus offiicinalis L.,and to evaluate its repellent effect.[Methods]The chemical components of the compound mosquito repellent essential oil were analyzed by gas chromatography-mass spectrometer(GC-MS),and the repellent activity of the essential oil against adult Aedes albopictus was evaluated according to the"Efficacy Test and Evaluation of Space Repellent Products(Y-tube Method)".[Results]Fifty-eight main volatile components were identified,accounting for 98.28％of the total components of essential oil,eighteen terpenes(44.99％),nine alkenes(20.27％),five esters(14.07％),eight aromatic hydrocarbons(12.00％),seven alkanes(3.48％),nine alcohols(2.78％),two ketones(0.69％).The percent repellency(PR)of the compound mosquito repellent essential oil against Aedes albopictus was more than 90％on average.[Conclusion]There were many chemical components in the compound mosquito repellent essential oil.There may be a variety of chemical components such as menthol,menthone,α-pinene,etc,which had a repellent effect on Aedes albopictus,and the average repellent effect reached the A level.

Menthae haplocalyx Briq.Spirodela polyrrhiza(L.)SchleidAcorus tatarinowii SchottRosmarinus officinalis L.compound mosquito repellent essential oilgas chromatography-mass spectrometerrepellent activity

程亮、施晨曦、周鑫、兰济乐、张盼盼、谢慧淼、沈晓霞、阮叶萍

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浙江中医药大学 杭州 310053

中药植物精油浙江省工程研究中心

浙江中医药大学芳香生物精油与疗法研究院

浙江中医药大学附属第二医院名中医馆

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薄荷 浮萍 石菖蒲 迷迭香 复方驱蚊精油 气质联用色谱技术 驱避性

国家级大学生创新创业训练计划项目国家级大学生创新创业训练计划项目省级大学生创新创业训练计划项目浙江中医药大学横向课题浙江中医药大学科研项目

202310344076X202210344045XS2022103441322021-HT-7922022JKXSY12

2024

10.16466/j.issn1005-5509.2024.02.003

浙江中医药大学学报
浙江中医药大学

浙江中医药大学学报

CSTPCD
影响因子：1.049
ISSN：1005-5509
年,卷(期)：2024.48(2)
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