Preparation and properties of efficiently translocated fludioxonil nanofungicide
In order to improve the targeted accumulation of fungicides on the lesion locations against Fusarium wilt in bananas,polymer nanocarriers(PSI-PHE)were constructed with polysuccinimide(PSI)and phenylalanine(PHE).Then fludioxonil(FLU)was loaded into the nanocarriers to produce PHE-guided nanoparticles(FLU@PSI-PHE).The infrared spectroscopy,hydrodynamic size,zeta potential,thermogravimetric analysis and X-ray diffraction analysis were explored to characterize the in-teraction and loading capacity between nanocarriers and FLU.The results showed that the loading capaci-ty of FLU@PSI-PHE nanoparticles with 531 nm by hydrodynamic size was up to 45.96%,and the trans-location dose of the castor phloem was 1.27 μg/mL,showing efficient phloem delivery effect.Compared with low doses of FLU,FLU@PSI-PHE nanoparticles with the same active ingredient content showed ba-sically equal antifungal activity against Fusarium wilt in bananas.Amino acid-mediated FLU@PSI-PHE could be efficiently translocated in plant vascular tissues,which provides new technology for targeted treatment of banana Fusarium wilt.