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珠三角杂交鳢源鰤鱼诺卡氏菌耐药性分析

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为了解广东省珠三角地区杂交鳢源鰤鱼诺卡氏菌耐药情况,课题组从2021年3月到2022年7月进行杂交鳢流行病学调查,共分离获得127株杂交鳢源病原菌,其中鰤鱼诺卡氏菌株42株,对有代表性的27株鰤鱼诺卡氏菌进行耐药性分析.结果显示,全年均可分离到鰤鱼诺卡氏菌,占全部分离菌株的33.1%;多数鰤鱼诺卡氏菌株体外对同一药物共同表现敏感或耐药,对β-内酰胺类完全耐药(100%),而对大环内酯类多数敏感(85.2%);其次,佛山地区部分菌株较中山地区菌株更为耐药,所有菌株均为多重耐药.杂交鳢鰤鱼诺卡氏菌整体耐药谱相似,多重耐药性情况较严重,佛山和中山地区部分菌株耐药性上存在一定差异.本研究为杂交鳢诺卡氏菌病精准用药提供参考.
Analysis of drug resistance of Nocardia seriolae from hybrid snakehead in Pearl River Delta
In order to understand the drug resistance of Nocardia seriolae from hybrid snakehead in the Pearl River Delta region of Guangdong Province,the research group conducted an epidemiological survey of hybrid snakehead from March 2021 to July 2022.A total of 127 strains of pathogenic bacteria were iso-lated from hybrid snakehead,including 42 strains of N.seriolae.The drug resistance of 27 strains of N.seriolae was analyzed.The results showed that N.seriolae could be isolated throughout the year,account-ing for 33.1%of all isolated strains.The majority of N.seriolae strains were sensitive or resistant to the same drug,e.g.completely resistant to β-lactams(100%),and sensitive to macrolides(85.2%).Some strains in Foshan area were more resistant than those in Zhongshan area,and all the strains were multi-drug resistant.The overall drug resistance spectrum of N.seriolae was similar,and the multi-drug resistance was serious.There were some differences in the drug resistance of some strains in Foshan and Zhongshan areas.This study provides a reference for the precise medication of hybrid snakehead nocardiosis.

hybrid snakeheadNocardia seriolaeisolationdrug resistance

马壮、江飚、孙龑鑫、温彩怡、张家豪、杨菁、苏友禄

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仲恺农业工程学院动物科技学院/动物健康养殖创新研究院,广东广州 510225

中山市三角镇农业服务中心,广东中山 528422

杂交鳢 鰤鱼诺卡氏菌 分离 耐药情况

2022年中央成品油价格调整对渔业补助预算资金

粤财农[2022]119号

2024

仲恺农业工程学院学报
仲恺农业工程学院

仲恺农业工程学院学报

影响因子:0.292
ISSN:1674-5663
年,卷(期):2024.37(2)