Research progress of biological markers for immunotherapy in patients with pancreatic cancer
Pancreatic cancer is one of the common gastrointestinal malignancies,the incidence of which is increasing year by year and has become one of the most important public health problems worldwide.At present,tumor treatment has entered the era of immunotherapy,but the response of pancreatic cancer patients to immune checkpoint inhibitors is not ideal.In addition,there is a lack of effective and validated biomarkers to stratify patients who may benefit from immunotherapy.This review has summarized the current research advances of immunotherapeutic biomarkers in pancreatic cancer,hoping to help clinicians understand relevant biomarkers systematically and guide the precise treatment of pancreatic cancer.