首页|影像学检查对乳腺癌患者腋窝淋巴结状态评估的研究进展

影像学检查对乳腺癌患者腋窝淋巴结状态评估的研究进展

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减少腋窝淋巴结的手术切除是乳腺癌外科治疗的明显趋势.近年来,随着Z0011、NSABP B-32和AMAROS等几项以外科手术为干预方式的前瞻性随机对照临床研究的10年数据的公布,腋窝淋巴结的清扫在越来越多的乳腺癌患者中得到了避免.然而,这些研究的入组标准均为临床评估腋窝淋巴结阴性的患者,经前哨淋巴结活检证实为无腋窝淋巴结转移或存在1~2个腋窝淋巴结阳性的患者.在术前如何准确预测并筛选出腋窝淋巴结阴性的患者,以减少对患者进行不必要的前哨淋巴结活检术,是目前乳腺癌外科领域仍需要解决的问题之一.乳腺X线摄影检查、超声成像、CT、MRI和PET-CT等影像学检查已被广泛应用于乳腺癌患者中,在腋窝淋巴结状态的术前评估方面也表现出很大的应用潜力.本文基于以上影像学检查手段对乳腺癌患者术前腋窝淋巴结状态评估的研究进展进行综述.
Advances in imaging examinations for axillary lymph node status assessment in breast cancer patients
The reduction in surgical axillary lymph node dissection has emerged as a notable trend in the surgical management of breast cancer.In the recent years,with the release of the ten-year data from prospective randomized controlled clinical trials,such as Z0011,NSABP B-32,and AMAROS,in which surgical intervention was primarily utilized,an increasing number of breast cancer patients have been spared from axillary lymph node dissection.Nevertheless,the inclusion criteria employed in these studies rooted in the clinical assessment of axillary lymph node-negative patients who were subsequently validated through sentinel lymph node biopsy,confirming the absence of axillary lymph node metastasis or the presence of 1-2 positive axillary lymph nodes.The accurate preoperative prediction and selection of axillary lymph node-negative patients,with the aim of minimizing unnecessary sentinel lymph node biopsy,continues to be a pertinent concern within the realm of breast cancer surgery.Diverse imaging modalities,including mammography,ultrasound imaging,CT,MRI,and PET-CT,have been widely adopted in the evaluation of breast cancer patients,showing substantial potential in the preoperative assessment of axillary lymph node status.This review provides an overview of the advancement in preoperative axillary lymph node status assessment for breast cancer patients using these imaging techniques.

Breast cancerAxillary lymph nodeImaging examination

李玲、潘战宇

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天津医科大学肿瘤医院,国家恶性肿瘤临床医学研究中心,天津市恶性肿瘤临床医学研究中心,乳腺癌防治教育部重点实验室,天津 300060

乳腺癌 腋窝淋巴结 影像学检查

2024

肿瘤
上海市肿瘤研究所

肿瘤

CSTPCD
影响因子:1.112
ISSN:1000-7431
年,卷(期):2024.44(3)