Advances in imaging examinations for axillary lymph node status assessment in breast cancer patients
The reduction in surgical axillary lymph node dissection has emerged as a notable trend in the surgical management of breast cancer.In the recent years,with the release of the ten-year data from prospective randomized controlled clinical trials,such as Z0011,NSABP B-32,and AMAROS,in which surgical intervention was primarily utilized,an increasing number of breast cancer patients have been spared from axillary lymph node dissection.Nevertheless,the inclusion criteria employed in these studies rooted in the clinical assessment of axillary lymph node-negative patients who were subsequently validated through sentinel lymph node biopsy,confirming the absence of axillary lymph node metastasis or the presence of 1-2 positive axillary lymph nodes.The accurate preoperative prediction and selection of axillary lymph node-negative patients,with the aim of minimizing unnecessary sentinel lymph node biopsy,continues to be a pertinent concern within the realm of breast cancer surgery.Diverse imaging modalities,including mammography,ultrasound imaging,CT,MRI,and PET-CT,have been widely adopted in the evaluation of breast cancer patients,showing substantial potential in the preoperative assessment of axillary lymph node status.This review provides an overview of the advancement in preoperative axillary lymph node status assessment for breast cancer patients using these imaging techniques.
Breast cancerAxillary lymph nodeImaging examination