Liver metastasis of uveal melanoma:mechanism and treatment strategy
Uveal melanoma originates from the uveal tract and has a significant tendency to liver metastasis.Once metastasis occurs,the prognosis is poor.The current treatment options for uveal melanoma are liver-directed therapies including liver partial resection,ablation,isolated hepatic perfusion and percutaneous hepatic perfusion,hepatic artery infusion chemotherapy,transcatheter arterial chemoembolization,immune embolization,and radioembolization,and systemic treatment for metastatic uveal melanoma.This review discusses the pathogenesis of liver metastasis in uveal melanoma and reviews the current treatment options for uveal melanoma.
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