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恶性实体瘤手术患儿围手术期的营养状态及相关危险因素

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目的 调查恶性实体瘤手术患儿围手术期营养状态及其危险因素.方法 选取海南省妇女儿童医学中心 2020 年 3月至 2023 年 3 月收治的 60 例恶性实体瘤手术患儿,按术后 3 个月营养状况分为营养不良组和无营养不良组,分析恶性实体瘤手术患儿围手术期营养状态及其营养不良的危险因素.结果 术后 3 个月,60 例恶性实体瘤手术患儿中无营养不良 32 例(53.33%)、营养不良 28 例(46.67%).营养不良组患儿体质量指数(BMI)、去脂体质指数(FFMI)、身体细胞质量指数(BC-MI)低于无营养不良组,脂肪质量指数(FMI)明显高于无营养不良组(P=0.005、P=0.004、P<0.001、P=0.007).相比无营养不良组,营养不良组术后放化疗、入院时营养状况为中高风险占比明显更高,住院期间膳食摄入符合标准、特殊营养治疗占比明显更低,差异有统计学意义(P<0.001、P=0.001、P<0.001、P=0.006).术后放化疗、入院时营养状况是恶性实体瘤手术患儿营养不良的危险因素(P=0.017、P=0.029).结论 恶性实体瘤手术患儿围手术期营养状况差,术后营养不良风险较高,需加强对入院时营养状况不佳及术后放化疗患儿的营养治疗.
Perioperative nutritional status of children undergoing operation for malignant solid tumors and its risk factors
Objective To investigate the perioperative nutritional status of children undergoing operation for malignant solid tumors and its risk factors.Method A total of 60 children who underwent operation for malignant solid tumors at Hainan Women and Children's Medical Center from March 2020 to March 2023 were enrolled.They were divided into malnutrition group and non-malnutrition group according to the nutritional status in 3 months after operation.The perioperative nutritional status of children undergoing operation for malignant solid tumors and the risk factors for malnutrition were analyzed.into malnutrition group and no malnutrition group.The perioperative nutritional status and risk factors of malnutrition in children undergoing surgery for malignant solid tumors were analyzed.Result In 3 months after operation,there were 32(53.33%)children without malnutrition and 28(46.67%)children with malnutrition.BMI,FFMI and BCMI in the malnutrition group were lower,and FMI was significantly higher as compared with the non-malnutrition group(P=0.005,P=0.004,P<0.001,P=0.007).Compared with the non-malnutrition group,the proportions of children undergoing radiotherapy and chemotherapy after operation,and children with medium-risk and high-risk nutritional status at admission were significantly higher.During hospitalization,the dietary intake meets the standards and the proportion of special nutritional support is significantly lower in the malnutrition group(P<0.001,P = 0.001,P<0.001,P = 0.006).Postoperative radiotherapy and chemotherapy and nutritional status at admission were risk factors for malnutrition in children undergoing operation for malignant solid tumors(P= 0.017,P= 0.029).Conclusion The perioperative nutritional status of children undergoing operation for malignant solid tumors is not good,and the risk of postoperative malnutrition is high.It is necessary to strengthen nutritional support for children with poor nutritional status at admission and those undergoing radiotherapy and chemotherapy after operation.

Malignant solid tumorChildPerioperative periodNutritional statusRisk factor

陆洁婷、张京、吴少晶、刘琪、陈春容、黄艾慧

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海南省妇女儿童医学中心普外肿瘤外科,海南 海口 570311

海南省妇女儿童医学中心临床营养科,海南 海口 570311

海南省妇女儿童医学中心血液肿瘤内科,海南海口 570311

恶性实体瘤 患儿 围手术期 营养状态 危险因素

海南省卫生健康行业科研项目海南省临床医学中心建设项目

21A200247琼卫医函[2021]75号

2024

肿瘤代谢与营养电子杂志

肿瘤代谢与营养电子杂志

CSTPCD
ISSN:
年,卷(期):2024.11(1)
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