Discussion on the role of albumin preparations in tumor nutritional therapy
Patients with malignant tumors often suffer from malnutrition due to chronic energy-protein depletion,insufficient intake of other nutrients in the body,and malabsorption,resulting in energy and protein deficiency.Serum albumin level is an important indicator to reflect the nutritional status of patients.Clinically,albumin preparations are often mistakenly used as nutrients in clinical practice.In fact,the nutritional supply of cancer patients should be based on amino acids and energy supplementation.This article analyzes the basic points of human nutritional requirements,metabolic changes,nutritional status classification and nutrient supply of cancer patients.And we discussed the principles,methods and classification of human nutrients and specific calculation methods of dosage supply;A variety of amino acid formulation types that can be provided clinically.The synthesis and distribution of albumin in vivo were analyzed in detail.The main role of serum albumin in the human body is to expand blood volume and maintain plasma osmolality,and it also has the biological function of non-osmotic pressure.The application history of albumin preparations and the clinical guidelines for albumin preparations in China and abroad are reviewed.The significance of albumin preparations in the application of various diseases is mainly used in shock caused by trauma and burns,edema and ascites caused by liver cirrhosis or kidney disease,cerebral edema,neonatal hyperbilirubinemia.The misunderstandings of the clinical application of human albumin preparations were analyzed.This article provides a theoretical basis for how to correctly provide nutrition for cancer patients and how to use albumin preparations correctly and rationally.
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