Objective This study aims to investigate the prevalence of sarcopenia specifically in Chinese patients with malignant tumors.Method A total of 61627 patients with 19 types of malignant tumors from 86 grade-A hospitals from July 2013 to December 2023 were included in the INSCOC database of the Chinese Tumor Nutrition Cohort Study.The diagnostic criteria for sarcopenia provided by the Asian Working Group on Sarcopenia (AWGS) in 2019 were used.Chi-square test or Fisher exact test was used to compare the prevalence of sarcopenia in patients with different population characteristics.Result The prevalence of sarcopenia in cancer patients was 18.1%.The prevalence of sarcopenia varied with tumor type,TNM stage,age,gender,administrative area and treatment.The prevalence of sarcopenia was higher in patients with digestive system cancers,and the highest prevalence was found in patients with pancreatic cancer[32.4%(311/961)].The prevalence of sarcopenia increased with the increase of TNM stage (P<0.05).The prevalence of sarcopenia was the highest in patients over 70 years old[34.7% (3510/10129)].The prevalence of sarcopenia in female cancer patients was higher than that in male patients[16.1%(5544/34381) vs 20.7%(5631/27246),P<0.05].The lowest prevalence was found in the Northeast region[14.7%(2398/16300)].Patients who received surgical treatment had the highest prevalence[22.1%(1635/7412)].In addition,in some tumor types,there were significant differences in the prevalence of sarcopenia among patients with different medical insurance types,occupation,education level,ethnicity,and place of residence.Patients with low education level and farmers had a higher risk of sarcopenia.Conclusion This study is the first to report the incidence of sarcopenia in tumor patients on a large scale,with a prevalence of 18%.Patients with digestive system cancers,elderly,farmers,low education level and advanced tumor are high risk groups for sarcopenia.
关键词
恶性肿瘤/肌肉减少症/四肢骨骼肌指数/现况调查/患病率/影响因素/老年/消化道系统
Key words
Malignant tumor/Sarcopenia/Appendicular skeletal muscle mass index/Current investigation/Prevalence/Influencing factors/Aged/Digestive system