Longitudinal study of prognostic nutritional index curve in patients with primary liver cancer
Objective To explore the change track of prognostic nutritional index in patients with primary liver cancer and analyze its influencing factors.Method 140 patients diagnosed with primary liver cancer who underwent surgical treatment in the Third People's Hospital of Nantong from January 2021 to December 2023 were selected as the study objects.General data questionnaire and nutritional index were used to investigate within one week after surgery (T1),after the first radiotherapy (T2),after 15 radiotherapy (T3),after 30 radiotherapy or after the last radiotherapy (T4) .Latent category growth model and single factor analysis were used for data processing.Result The prognostic nutritional index curve of patients with primary liver cancer was identified to be divided into three potential categories,and the average probability of patients in each category belonging to each potential category was 0.946,0.950,0.944,respectively.The three categories were malnutrition plus recombination (28.3％),good nutrition (55.8％) and improved malnutrition (15.9％).Different locus categories were age (x2=15.025,P=0.005),marital status (x2=7.407,P=0.025),education level (x2=16.364,P=0.012),liver cancer grade (x2=12.004,P=0.017),chronic disease (x2=7.887,P=0.012),the difference was statistically significant.Conclusion By investigating the change characteristics of prognostic nutritional index in patients with primary liver cancer from postoperative to the end of radiotherapy,this study identified three different curve trajectories,and there were differences in the curve trajectories of prognostic nutritional index in patients.Clinical staff should pay close attention to patients with primary liver cancer caused by malnutrition and recombination,timely identify high-risk patients with malnutrition,and provide active and targeted nutritional support to reduce the occurrence of adverse events caused by malnutrition as much as possible.
Primary liver cancerPrognostic nutritional indexCurveTrackLongitudinal studyInfluencing factorPotential catehoriesNutritional status
万方数据
维普
