首页|氧化平衡分数与牙周炎的关系:基于美国国家健康和营养调查2009—2012年的研究

氧化平衡分数与牙周炎的关系:基于美国国家健康和营养调查2009—2012年的研究

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目的 探索在全人群或肿瘤患者中氧化平衡分数(OBS)与牙周炎的关系.方法 回顾性分析2009—2012年美国国家健康和营养调查数据库中5980例参与者的临床资料.限制性立方样条图被用来描述OBS与牙周炎风险的非线性关系.Logistic回归分析被用来描述在全人群和肿瘤人群中OBS、OBS饮食及OBS生活方式与牙周炎风险的关系,并用OR和95%CI表示.亚组分析和交互作用分析被用来探索OBS及其成分与牙周炎的关系在不同组间的情况.结果 共有5980例参与者纳入到本研究中,平均年龄为(51.91±14.19)岁,其中3301例参与者存在牙周炎.与低OBS的参与者相比,高OBS的参与者的牙周炎风险降低(OR=0.80,95%CI=0.68~0.93),在肿瘤患者中,这项关系更加明显(OR=0.66,95%CI=0.48~0.89).亚组分析和交互作用分析结果显示,OBS与牙周炎的关系受到年龄的影响,年龄≥65岁的参与者中,OBS的保护作用更强(OR=0.61,95%CI=0.43~0.87).结论 OBS的升高降低牙周炎的发生风险,尤其是在肿瘤患者中.此外,这项关系还受到年龄的影响,在老年人中,OBS升高显著降低牙周炎风险.改善OBS相关的饮食模式和生活方式可能有助于降低牙周炎的发生风险.
The relationship between oxidative balance score and periodontitis:a study based on National Health and Nutrition Examination Survey 2009-2012
Objective To explore the relationship between the oxidative balance score (OBS) and periodontitis.Method A retrospective analysis of clinical data from 5980 participants in the National Health and Nutrition Examination Survey(NHANES) database from 2009 to 2012 was conducted.We described the nonlinear relationship between OBS and the risk of periodontitis using restricted cubic splines.Logistic regression analysis was used to further describe the association between OBS and its components with the risk of periodontitis.Subgroup and interaction analyses were employed to explore this relationship across different groups.Result The study included 5980 patients,with an average age of (51.91±14.19) years.Of these,3301 participants had periodontitis.Compared to participants with a low OBS,those with a high OBS had a reduced risk of periodontitis(OR=0.80,95%CI=0.68-0.93).In patients with cancer,this relationship was more pronounced (OR=0.66,95%CI=0.48-0.89).Subgroup and interaction analysis showed that the relationship between OBS and periodontitis was moderated by age,with a stronger protective effect of OBS observed in older participants(age ≥ 65 years)(OR=0.61,95%CI=0.43-0.87).Conclusion This study indicates that an increased OBS is associated with a reduced risk of periodontitis,and this relationship is influenced by age.In older individuals,a higher OBS has a stronger protective effect against the risk of periodontitis.Improving OBS-related diet and lifestyle may help reduce the occurrence and progression of periodontitis.

PeriodontitisOxidative balance scoreCross-sectional studyNational Health and Nutrition Examination SurveyDietary patternsTumorAging

王泽琛、王珊珊、刘静思、栗兴超

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河北医科大学口腔医院口腔颌面外科,河北石家庄 050001

张家口市肺科医院内一科,河北张家口 075001

河北医科大学口腔医院修复科,河北石家庄 050001

牙周炎 氧化平衡分数 横断面研究 美国国家健康和营养调查数据库 饮食模式 生活方式 肿瘤 衰老

2024

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CSTPCD
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年,卷(期):2024.11(5)