首页|HER2阳性乳腺癌治疗中蒽环类药物应用的研究进展

HER2阳性乳腺癌治疗中蒽环类药物应用的研究进展

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蒽环类药物是乳腺癌治疗的基石之一,鉴于蒽环类药物令人担忧的心脏毒性限制以及抗人表皮生长因子受体2(human epidermal growth factor receptor 2,HER2)治疗药物的发展,导致蒽环类药物在HER2阳性乳腺癌新辅助和辅助治疗中的地位受到挑战.全文从HER2阳性乳腺癌新辅助和辅助治疗的临床研究中探讨蒽环类药物的"去留"作一综述.
Research Progress on Anthracycline in the Treatment of HER2 Positive Breast Cancer
The application of anthracyclic drugs is one of the cornerstones of breast cancer treat-ment.However,the status of anthracycline drugs in the new adjuvant and adjuvant treatment of human epidermal growth factor receptor 2(HER2)positive breast cancer is facing a challenge at present,due to its cardiac toxicity and the development of new anti-HER2 drugs.This paper dis-cusses the"fate"of anthracycline drugs in new adjuvant and adjuvant treatment of HER2 positive breast cancer,bases on the recent research evidence and evidence-based medicine.

breast cancerHER2anthracyclineneoadjuvant therapyadjuvant therapy

董孟浩、魏文慧、单本杰、王金男、潘跃银

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中国科学技术大学附属第一医院,安徽合肥 230000

乳腺癌 HER2 蒽环 新辅助治疗 辅助治疗

安徽省重点研究与开发计划

202104j07020040

2024

肿瘤学杂志
浙江省肿瘤医院 浙江省抗癌协会

肿瘤学杂志

CSTPCD
影响因子:0.83
ISSN:1671-170X
年,卷(期):2024.30(1)
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