Advances on Application of Metabolomics in Cancer Research
Metabolomics is a systematic study of the composition and changes of metabolites in the organism using high-throughput technique to explore their roles and regulatory mechanism.Metabolic reprogramming is one of the major hallmarks of malignant tumors.During the tumori-gensis and progression,metabolic profiles in the organism undergo significant alterations,there-fore metabolomics is an important tool in cancer research.In recent years,metabolomics tech-niques have been widely applied in cancer research,including cancer screening,early diagnosis,efficacy prediction,prognosis evaluation,and new drug targets identification.This paper reviews the recent advances of metabolomics in cancer research focusing on the potential value of metabolomics techniques in clinical application.