Research Progress on Screening and Prevention of Hereditary Breast Cancer
Hereditary breast cancer is associated with pathogenic germline mutations of suscepti-bility genes such as BRCA1/2,which increase the lifetime risk of breast cancer.Early detection of high risk individuals has become an important breakthrough in screening and prevention of hered-itary breast cancer,while the advancements in screening techniques make it possible.This paper reviews the state quo of screening and prevention of hereditary breast cancer in China and abroad,focusing on risk assessment,genetic testing,and genetic counseling for patients with hereditary breast cancer.
hereditary breast cancerBRCA1/2germline mutationscreeningprevention
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