Research Progress on Ferroptosis-Related Gene MTDH in Regulation of Breast Cancer
Breast cancer,as the leading cancer threatening women's health,requires constant updates and improvements in treatment strategies.MTDH,as a driver gene in ferroptosis,has po-tential therapeutic value in breast cancer.This paper reviews the role of MTDH in the metastasis and drug resistance of breast cancer,immune microenvironment,cancer stemness,and its cor-relation with ferroptosis.It demonstrates that MTDH,as a specific target for breast cancer treat-ment,has tremendous potential,but lacks sufficient clinical research data.Therefore,a thorough exploration of the relationship of MTDH with breast cancer and its immunity is expected to iden-tify novel treatment methods to overcome the drug resistance and improve the prognosis of breast cancer patients.
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