外周血炎性指标评估肝细胞癌预后的研究进展
Research Progress on the Prognostic Value of Peripheral Blood Inflammatory Markers in Hepatocellular Carcinoma
刘小非 1石柴琴 1苏涵 1鲁思怡 1罗利琼2
作者信息
- 1. 武汉科技大学第一临床学院,湖北 武汉 430064
- 2. 武汉科技大学附属天佑医院,湖北 武汉 430064
- 折叠
摘要
炎症已被证明在肿瘤形成过程中起重要作用,可促进肿瘤细胞侵袭转移等行为,与肿瘤生长加速、淋巴结转移和总体不良预后相关.因此,反映全身炎症反应的指标,如血小板与淋巴细胞比值、中性粒细胞与淋巴细胞比值、预后营养指数、全身免疫炎症指数等评分作为肝细胞癌患者的预后因素具有潜在价值,且已有多项研究证明炎性指标可作为肝细胞癌的独立预后因子.全文总结上述外周血炎性指标在评估肝细胞癌预后价值中的研究进展,旨在为临床实践提供一定参考价值.
Abstract
Inflammation plays a crucial role in tumor occurrence,development,invasion and metastasis,and is associated with the overall prognosis of patients.Therefore,inflammatory indi-cators,such as platelet and lymphocyte ratio(PLR),neutrophils and lymphocytes ratio(NLR),prognosis of nutrition index(PNI),and systemic immune inflammation index(SII),have potential value in prognosis of cancer patients.Numerous studies have demonstrated that inflammatory markers can serve as independent prognostic factors for patients with hepatocellular carcinoma.This paper reviews the research progress on the value of peripheral blood inflammatory markers in the prognosis of hepatocellular carcinoma,aiming to provide references for clinical practice.
关键词
肝细胞癌/血小板与淋巴细胞比值/中性粒细胞与淋巴细胞比值/预后营养指数/全身免疫炎症指数Key words
hepatocellular carcinoma/platelet to lymphocyte ratio/neutrophil to lymphocyte ratio/prognostic nutritional index/systemic immune inflammation index引用本文复制引用
出版年
2024
NETL
NSTL
万方数据