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外周血炎性指标评估肝细胞癌预后的研究进展

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炎症已被证明在肿瘤形成过程中起重要作用,可促进肿瘤细胞侵袭转移等行为,与肿瘤生长加速、淋巴结转移和总体不良预后相关.因此,反映全身炎症反应的指标,如血小板与淋巴细胞比值、中性粒细胞与淋巴细胞比值、预后营养指数、全身免疫炎症指数等评分作为肝细胞癌患者的预后因素具有潜在价值,且已有多项研究证明炎性指标可作为肝细胞癌的独立预后因子.全文总结上述外周血炎性指标在评估肝细胞癌预后价值中的研究进展,旨在为临床实践提供一定参考价值.
Research Progress on the Prognostic Value of Peripheral Blood Inflammatory Markers in Hepatocellular Carcinoma
Inflammation plays a crucial role in tumor occurrence,development,invasion and metastasis,and is associated with the overall prognosis of patients.Therefore,inflammatory indi-cators,such as platelet and lymphocyte ratio(PLR),neutrophils and lymphocytes ratio(NLR),prognosis of nutrition index(PNI),and systemic immune inflammation index(SII),have potential value in prognosis of cancer patients.Numerous studies have demonstrated that inflammatory markers can serve as independent prognostic factors for patients with hepatocellular carcinoma.This paper reviews the research progress on the value of peripheral blood inflammatory markers in the prognosis of hepatocellular carcinoma,aiming to provide references for clinical practice.

hepatocellular carcinomaplatelet to lymphocyte rationeutrophil to lymphocyte ratioprognostic nutritional indexsystemic immune inflammation index

刘小非、石柴琴、苏涵、鲁思怡、罗利琼

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武汉科技大学第一临床学院,湖北 武汉 430064

武汉科技大学附属天佑医院,湖北 武汉 430064

肝细胞癌 血小板与淋巴细胞比值 中性粒细胞与淋巴细胞比值 预后营养指数 全身免疫炎症指数

2024

肿瘤学杂志
浙江省肿瘤医院 浙江省抗癌协会

肿瘤学杂志

CSTPCD
影响因子:0.83
ISSN:1671-170X
年,卷(期):2024.30(9)
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