Application Value of Fluorescence Localization with Indocyanine Green in Single-Port Thoracoscopic Resection of Pulmonary Nodules
[Objective]To explore the application value of CT-guided percutaneous fluorescence localization with indocyanine green(ICG)in single-port thoracoscopic resection of pulmonary nodules.[Methods]The clinical data of 100 patients who underwent single-port thoracoscopic resection of pulmonary nodu-les in Department of Thoracic Surgery of the First Affiliated Hospital of Ningbo University from Febru-ary 2022 to December 2023 were retrospectively analyzed.The localization of pulmonary nodules was performed before surgery,48 cases underwent CT-guided percutaneous Hookwire localization(control group)and 52 cases underwent CT-guided percutaneous ICG localization and fluorescence thoracoscopic surgery(study group).The clinical data,localization time,localization success rate,localization com-plications and other perioperative indicators were compared between two groups with SPSS21.0 software.[Results]There was no significant difference in localization success rate,localization time,pleural re-action,intraoperative pulmonary hemorrhage and localization-related hemothorax between two groups(all P>0.05).The pain score after localization in the study group was significantly lower than that in the control group[2(2,2)vs 4(4,5),P<0.001],and the incidence of pneumothorax after localization in the study group was lower than that in the control group(7.7%vs 31.2%,P=0.003).The incidence of cough during the operation in the study group was significantly higher than that in the control group(92.3%vs 8.3%,P<0.001).There was no significant difference in operation time,surgical procedure type,pleural adhesion,intraoperative blood loss,postoperative chest tube duration,postoperative hos-pital stay,and postoperative pathological results between two groups(P>0.05).[Conclusion]ICG local-ization of pulmonary nodules is simple and effective,with high success rate,long maintenance time af-ter localization,less pain,good safety and few adverse reactions,which is especially advantageous for patients who need to locate multiple nodules and is worthy of promotion and application.