Direct electrochemical determination of baicalein based on gold nanoparticles modified carbon fiber microelectrode
AuNPs with small particle size were prepared by reducing chloroauric acid with trisodium citrate,and then modified on the surface of CFME by potentiostatic deposition to construct a highly sensitive and selective electrochemical sensor.The sensor and modified material were characterized by transmission electron microscope,scanning electron microscope and UV spectrophotometry,the electrochemical properties of baicalein on electrode before and after modification were investigated bydifferential pulse voltammetry,cyclic voltammetry and electrochemical impedance spectroscopy,the determination conditions such as scan rate,buffer pH and electrodeposition time were optimized.The results showed that AuNPs had significant electrocatalytic performance to baicalein,and the optimal modification time was 10 min.The oxidation peak current and concentration of baicalein showed good linear relationship between 0.05-10 µmol/L,and the linear regression equation were Ip(nA)=0.4409C(µmol/L)+0.7066,R2=0.998.The method has fast response and good stability,which can be used for quantitative detection of baicalein.
国家科技期刊平台
NSTL
万方数据
维普
