Preparation and process optimization of Qiai oil-β-cyclodextrin inclusion complex film
In order to improve the utilization of volatile oil,the optimal process of Qiai oil-β-cyclodextrin inclusion complex film using β-cyclodextrin to encapsulate volatile oil was investigated,followed by sodium carboxymethyl cellulose as the film-forming material.Qiai oil-β-cyclodextrin inclusion complex was prepared by saturated aqueous solution method.The effect of Qiai oil dosage,β-cyclodextrin dosage,sodium carboxymethyl cellulose concentration and glycerol dosage on the film formation process was investigated by orthogonal tests using appearance evaluation,film properties,properties of removing film and degree of skin fitting as characterization evaluation indexes.Results:The best film formation process for Qiai oil-β-cyclodextrin inclusion complex film is:1.5 mL of Qiai oil,10 g of β-cyclodextrin,1∶20(W/V,g-mL-1)of sodium carboxymethyl cellulose∶deionized water,6 mL of glycerol and fixed to 100 mL with deionized water.Conclusion:The optimized film-forming process is simple,stable and feasible,which providing an experimental basis for the development of Qiai antibacterial film agent.
Qiai oilβ-cyclodextrinCMC-Napreparationtechnique optimizationfilm forming process
万方数据
