Study on Structure Design and Optimization of Multi-channel Switching Ceramic Valve for Space Cell Culture
In order to meet the demand of long-term automatic cell culture in space station environ-ment,a new type of automatic cell culture device was developed.It was mainly composed of micro-pump and multi-channel switching valve.By designing a multi-channel switching ceramic valve,multiple liquid paths could be freely switched by only one pump and valve.Through finite element simulation analysis on the distribution of physical parameters such as pressure,temperature,and flow rate of three liquids,namely culture solution,digestion solution,and cracking solution,in the multi-channel switching valve,the optimal valve layout was determined and the valve body structure was optimized which improved the uniformity of distribution of different liquids after flowing into the valve chamber.After optimization,the pressure and temperature fluctuation rates of the cell culture medium and digestion medium in the multi-channel switching valve were both less than 1%,and the flow rate was stable.The temperature distribution variation of the cracking solution was 2℃before optimization,but less than 0.01℃after optimization,resulting in smoother liquid flow and reduced retention phenomenon.The simulation results showed that the optimized ceramic valve can help to improve the stability and economy of space cell culture.
space cell culturemulti-way switching valvecomputational fluid dynamicsfinite ele-ment analysisceramic valve