首页|急性心肌梗死患者中医证型及血压变异性与住院期间心血管事件的相关性研究

急性心肌梗死患者中医证型及血压变异性与住院期间心血管事件的相关性研究

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目的:探讨急性心肌梗死(AMI)患者中医证型及24h血压变异性(BPV)与住院期间主要心血管不良事件(MACE)的关系.方法:收集2023年5月—9月冠心病监护病房住院的AMI患者的临床资料.采用平均真实变异性(ARV)评估患者的BPV,计算24hARV.根据患者是否发生MACE分组,比较分析2组患者的年龄、性别、24hARV、中医证型、实验室指标等.以MACE为结局指标,采用Logistic回归分析AMI患者24hARV与MACE之间的关系.结果:本研究AMI患者中医证型分布由多到少依次为:气虚血瘀、气阴两虚、痰瘀互结、气滞血瘀和寒凝心脉.与痰瘀互结组、气滞血瘀组相比,气虚血瘀组、气阴两虚组的MACE发生率存在统计学差异(P<0.05).Logistic分析显示24h收缩压ARV和舒张压ARV与AMI患者住院期间MACE发生的相关性无统计学意义(P>0.05).结论:气虚血瘀证是AMI患者的主要证型,虚证AMI患者更易发生MACE.
The relationship between traditional Chinese medicine syndrome types,blood pressure variability,and cardiovascular events during hospitalization in patients with acute myocardial infarction
Objective:To explore the relationship between traditional Chinese medicine syndrome types,24-hour blood pressure variability(BPV),and major adverse cardiovascular events(MACE)during hospitalization in patients with acute myocardial infarction(A MI).Methods:We extracted clinical data of patients with AMI ad-mitted to the Coronary Heart Disease Intensive Care Unit,assessed BPV by using the average real variability(ARV),and calculated 24-hour ARV(24hARV)based on patients'blood pressure data on the first day of ad-mission.The patients were divided into MACE group and N-MACE group based on whether they had MACE.We explored whether there were differences in age,sex,24hARV,traditional Chinese medicine syndrome types,and laboratory indicators between the two groups of patients.Using MACE as the outcome indicator,logistic re-gression analysis was adopted to analyze the relationship between 24hARV and MACE in patients with AMI.Results:The distribution of traditional Chinese medicine syndrome types in AMI patients was as follows:Qi de-ficiency and blood stasis>Qi yin deficiency>Phlegm and blood stasis intertwined>Qi stagnation and blood stasis>Cold coagulation of heart meridians.There was a statistical difference in the incidence of MACE between the Qi deficiency and blood stasis group and the Qi yin deficiency and blood stasis group(P<0.05)compared to the phlegm stasis group and the Qi stagnation and blood stasis group.There were no significant correlation be-tween 24-hour systolic blood pressure ARV(24hSBPARV)and diastolic blood pressure ARV(24hDBPARV)and the incidence of MACE during hospitalization in patients with AMI(P>0.05).Conclusion:Qi deficiency and blood stasis syndrome is the main syndrome type of patients with AMI,and AMI patients with deficiency syn-drome are more prone to MACE.

acute myocardial infarctiontraditional Chinese medicine syndrome typeblood pressure variabili-tycardiovascular events

刘颖、安硕研、李问、黑梦雪、陈改玲

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北京中医药大学,北京 100029

中日友好医院 心脏科,北京 100029

新疆医科大学第二临床医学院,新疆乌鲁木齐 830011

急性心肌梗死 中医证型 血压变异性 心血管事件

2024

中日友好医院学报
中日友好医院

中日友好医院学报

CSTPCD
影响因子:0.92
ISSN:1001-0025
年,卷(期):2024.38(1)
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