首页|睡眠结构与原发性高血压的相关性初探

睡眠结构与原发性高血压的相关性初探

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目的:采用心肺耦合(CPC)睡眠分析技术探讨子时丑时睡眠结构与原发性高血压的相关性.方法:纳入2020年1月—2022年12月就诊于中日友好医院国际部的199例患者,根据24h动态血压监测(ABPM)结果将其分为高血压组和正常血压组,分析2组间子时丑时睡眠结构差异;根据CPC监测的睡眠质量评分,将患者分为睡眠质量良好组、一般组、较差组,分析3组患者间子时丑时睡眠结构的差异.结果:与正常血压组相比,高血压组患者子时丑时睡眠时长缩短、熟睡占比减少,差异具有统计学意义(P<0.05).整夜睡眠质量较差组患者的子时丑时熟睡占比少于良好和一般组,且子时丑时呼吸紊乱指数高于良好组和一般组,差异具有统计学意义(P<0.05).多因素Logistic回归结果显示,子时丑时熟睡占比减少(<0.75)是导致原发性高血压的危险因素(OR=1.661,P=0.023).结论:子时丑时睡眠结构异常可能是原发性高血压发病的危险因素.
The relationship between sleep structure and essential hypertension
Objective:To explore the correlation between sleep structure from the period of the day from 11 p.m.to 3 a.m.and essential hypertension by using the cardiopulmonary coupling(CPC)sleep analysis technology.Methods:A total of 199 patients were included in this study who were admitted to the International Depart-ment of China-Japan Friendship Hospital from January 2020 to December 2022.According to the results of 24h ambulatory blood pressure monitoring(ABPM),the subjects were divided into hypertension group and nor-mal blood pressure group.The difference of sleep structures during 11 p.m.to 3 a.m.between the two groups was analyzed.The subjects were divided into three groups:good sleep quality group,average sleep quality group and poor sleep quality group according to the overnight sleep quality score obtained from CPC,and the distribution difference of sleep structures among the three groups was analyzed.Results:Compared with normal blood pressure group,hypertension group had a significant difference in the shonened sleep duration and the proportion of deep sleep at 11 p.m.to 3 a.m.(P<0.05).The proportion of deep sleep in the group with poor sleep quality was less than that in the group with good and normal sleep quality,and RDI was higher than that in the group with good and normal sleep quality in one day at 11 p.m.to 3 a.m.(P<0.05).Multivariate logistic regression results showed that decreased sleeping proportion(<0.75)at 11 p.m.to 3 a.m.was a risk factor leading to essential hypertension.Conclusion:Abnormal sleep structure may be a risk factor affecting the incidence of essential hypertension.

cardiopulmonary coupling sleep analysissleep structureessential hypertension

李晨露、田秋慧、肖琦凡、张素巧、唐彬、朱宇清

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北京中医药大学中日友好临床医学院,北京 100029

重庆市江津区中医院肺病科,重庆 402260

中日友好医院 国际部全科医学科,北京 100029

心肺耦合睡眠分析 睡眠结构 原发性高血压

2024

中日友好医院学报
中日友好医院

中日友好医院学报

CSTPCD
影响因子:0.92
ISSN:1001-0025
年,卷(期):2024.38(3)
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